Effect of Simultaneous Cystectomy on Ovarian Reserve in Cases of Adnexal Detorsion

There are mostly ovarian cysts under adnexal torsion from gynecological emergencies. There are many studies in the literature examining the effect of adnexal detorsion on ovarian reserve. However, there is no study in the literature examining the effect of concomitant cystectomy. In this study, the investigators aimed to investigate whether the cystectomy procedure performed together with detorsion has an additional effect on the ovarian reserve in cases of ovarian torsion with cysts.

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Key information

Conditions

Ovarian Torsion Adnexal Diseases Endocrine System Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Gonadal Disorders Ovarian Diseases Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Torsion Abnormality Urogenital Diseases

Age range

15 year–63 year

Sex eligibility

Female

Study type

Observational

Primary location

Bagcilar Teaching and Research Hospital

Istanbul, Bagcilar, 34200, Turkey (Türkiye)

About this study

All women who underwent emergency surgery in the investigators' obstetrics and gynecology department since April 2015 due to adnexal torsion were analyzed. All patients who underwent ovarian detorsion (Group 1) and ovarian detorsion+cystectomy (Group 2) were called for control between 6-12 months postoperatively. In all patients, the sizes of both ovaries and the number of antral follicles were counted by ultrasonography by 2 physicians who did not know the detorsion side beforehand. All women will be compared within and between groups in terms of ovarian sizes and antral follicle numbers.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All women who underwent emergency surgery for ovarian torsion

Exclusion criteria

Those who underwent oophorectomy with suspicion of malignancy
When faced with spontaneously amputated ovary due to chronic or acute torsion
Women with only salpinx torsion

Treatment and study plan

ultrasonography

Diagnostic Test

By performing transvaginal or transabdominal ultrasonography on women, ovarian volume will be calculated and antral follicle will be counted.

Primary outcomes

Ovarian volume difference between groups

Time frame: postoperative 6-12 months

To analyze whether there is a difference between the ovarian reserve parameters of women who underwent detorsion and detorsion+cystectomy. With ultrasonographic imaging, both ovaries will be evaluated for ovarian volume ( V = length × width × height × π/6) (cm3). Both the affected ovary will be compared with the contralateral ovary and the affected ovaries will be compared between groups.
The number of antral follicles difference between groups

Time frame: postoperative 6-12 months

To analyze whether there is a difference between the ovarian reserve parameters of women who underwent detorsion and detorsion+cystectomy. With ultrasonographic imaging, both ovaries will be evaluated for the number of antral follicles. Both the affected ovary will be compared with the contralateral ovary and the affected ovaries will be compared between groups.

Sponsors and collaborators

Lead sponsor

Bagcilar Training and Research Hospital

Other Gov

Registry information

Important dates

Study start: 2017
Primary completion: 2022
Study completion: 2022
First posted: Jan 27, 2023
Registry last updated: Jan 27, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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