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OpenTrials
Completed

NCT Number: NCT01294995

Effect of Short-term Chinese Tea-flavor Liquor Consumption

Human studies of Chinese liquor are sparse. The investigators hypothesize that short-term Chinese Tea-flavor liquor (TFL) consumption may be beneficial to inflammation biomarkers and CVD risk factors. Guizhou Meijiao Liquor (GML) is a traditional Chinese liquor, fermented from sorghum, corn, sticky rice, wheat and rice, while TFL is a novel Chinese liquor fermented from above 5 grains plus green tea.

Forty-five volunteers(23 males, 22 females) were selected to participate a paralleled randomized trial drinking 30 mL two kinds of Chinese liquors: TFL and GML respectively with meal every day for 28 days. Serums of volunteers were collected for analyzing serum lipids, inflammation biomarkers and CVD risk factors.

TFL could significantly decrease systolic blood pressure of males, but increase diastolic blood pressure of females. TFL could also decreased blood lipid of volunteers, especially for females. Both liquor significantly decrease serum uric acid and glucose in males and females. The effect of the two liquors on inflammation biomarkers were complicated and needs further research work.

TFL may possess more beneficial effect on CVD risk factors than GML probably because of the special fermentation products of green tea with other grains.

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Key information

Age range

23 year–28 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Department of food science and nutrition

Hangzhou, Zhejiang, 310029, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy male and female volunteers

Exclusion criteria

  • Subjects with a history of liver disease, diabetes, or heart disease
  • Smokers

Treatment and study plan

Tea-flavor Liquor

Dietary Supplement

30 mL of Tea-flavor Liquor(45% alcohol content)

Guizhou Meijiao Liquor

Dietary Supplement

30 mL of Guizhou Meijiao Liquor (45% alcohol content)

Sponsors and collaborators

Lead sponsor

Zhejiang University

Other

Collaborators

  • Guizhou Meijiao Co., Ltd

Registry information

Official study title

Phase 1 Study of Chinese Tea-flavor Liquor

Acronym: ESTCTFLC

Important dates

Study start
2010
Primary completion
2010
Study completion
2010
First posted
Feb 14, 2011
Registry last updated
Feb 14, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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