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NCT Number: NCT07481279

Effect of Scoliosis and Progressive Resistance Exercises on Clinical and Pulmonary Parameters in Adolescents With Idiopathic Scoliosis

Adolescent idiopathic scoliosis (AIS) is a common spinal deformity that may affect physical function and pulmonary capacity during adolescence. Exercise-based rehabilitation programs are frequently used in the conservative management of scoliosis.

The aim of this study is to investigate the effects of scoliosis-specific exercises combined with upper and lower extremity progressive resistance exercises on anthropometric, clinical, and pulmonary parameters in adolescents with idiopathic scoliosis.

Participants diagnosed with adolescent idiopathic scoliosis will participate in an exercise program including scoliosis-specific exercises and progressive resistance exercises targeting upper and lower extremities. Anthropometric measurements, clinical assessments, and pulmonary function parameters will be evaluated before and after the intervention.

The results of this study are expected to provide evidence regarding the effectiveness of combined exercise interventions on physical and respiratory outcomes in adolescents with idiopathic scoliosis.

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Key information

Conditions

Adolescent Idiopathic Scoliosis (AIS) Bone Diseases Musculoskeletal Diseases Scoliosis Spinal Curvatures Spinal Diseases

Age range

12 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ankara Bilkent City Hospital

Ankara, Turkey (Türkiye)

About this study

Adolescent idiopathic scoliosis (AIS) is characterized by a three-dimensional spinal deformity that can influence posture, musculoskeletal balance, and respiratory function. Conservative treatment approaches often include physiotherapy-based exercise programs aimed at improving spinal alignment, muscle strength, and overall functional capacity.

In this study, adolescents diagnosed with idiopathic scoliosis will undergo an exercise intervention consisting of scoliosis-specific exercises combined with progressive resistance exercises targeting upper and lower extremity muscle groups. The intervention program aims to improve musculoskeletal strength, posture, and respiratory function.

Anthropometric measurements, clinical parameters, and pulmonary function values will be assessed before and after the exercise program. These outcomes will help evaluate the effectiveness of the intervention in improving physical and respiratory parameters in adolescents with idiopathic scoliosis.

The findings of this study may contribute to the development of effective rehabilitation strategies for adolescents with idiopathic scoliosis and support evidence-based physiotherapy practices.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adolescents aged between 12 and 18 years diagnosed with adolescent idiopathic scoliosis (AIS)
  • Cobb angle between 10° and 25° confirmed by radiological evaluation
  • C-type scoliosis curve pattern

Exclusion criteria

  • Presence of congenital scoliosis
  • Presence of chromosomal abnormalities
  • Presence of skeletal dysplasia
  • Presence of connective tissue disease
  • Presence of neuromuscular disease
  • Presence of metabolic diseases affecting bone metabolism
  • Calcium metabolism disorders
  • Severe autoimmune diseases
  • Severe endocrine diseases
  • Severe cognitive impairment
  • Orthopedic conditions preventing participation in exercise
  • History of spinal surgery
  • History of excisional procedure or surgery involving paravertebral muscles

Treatment and study plan

Scoliosis Exercises

Behavioral

Scoliosis-specific exercise program designed to improve spinal alignment, posture, and respiratory function in adolescents with idiopathic scoliosis. The program includes supervised therapeutic exercises performed under physiotherapist guidance.

Progressive Resistance Exercises

Behavioral

Progressive resistance exercise program targeting upper and lower extremity muscle groups including biceps, triceps, pectoral, back, quadriceps, and hamstring muscles.

Primary outcomes

  1. Muscle Thickness Measured by Ultrasonography

    Time frame: Baseline (Week 0), Week 4, and Week 8

    Changes in diaphragm, lumbar multifidus and pectoralis major muscle thickness measured by ultrasonography.

Secondary outcomes

  1. Sit and Reach Flexibility Test

    Time frame: Baseline (Week 0), Week 4, and Week 8

    Flexibility assessment using the sit and reach test to evaluate hamstring and lower back flexibility before and after the intervention.

  2. Back Scratch Test

    Time frame: Baseline (Week 0), Week 4, and Week 8

    Shoulder flexibility assessment using the back scratch test before and after the intervention.

  3. Hand Grip Strength

    Time frame: Baseline (Week 0), Week 4, and Week 8

    Upper extremity muscle strength measured using a hand dynamometer.

  4. Pulmonary Function Test

    Time frame: Baseline (Week 0), Week 4, and Week 8

    Pulmonary function parameters including FVC and FEV1 measured using spirometry.

Sponsors and collaborators

Lead sponsor

Ankara City Hospital Bilkent

Other

Registry information

Official study title

Effects of Scoliosis Exercises and Upper and Lower Extremity Progressive Resistance Exercises on Anthropometric, Clinical, and Pulmonary Parameters in Adolescents With Idiopathic Scoliosis

Acronym: SPRE-AIS

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Mar 18, 2026
Registry last updated
Apr 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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