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NCT Number: NCT06835842

Effect of Rib Mobilization on Weaning Parameters From Mechanical Ventilator in Patients With Pneumonia

this study will be conducted to distinguish between effect of rib mobilization and routine chest physiotherapy on weaning parameters from mechanical ventilator in patients with pneumonia •

HYPOTHESES:

It will be hypothesized that there may be significant effect of rib mobilization on weaning parameters from mechanical ventilator in patients with pneumonia.

RESEARCH QUESTION:

Does rib mobilization have an effect on weaning parameters from mechanical ventilator in patients with pneumonia? measuring weaning parameters: on screen of mechanical ventilator : measuring respiratory rate, Tidal volume (TV), FiO2.

* Arterial blood gases (ABG) analyzer machine ABG is recorded daily (PH- PaO2 - PaCO2) * Length of ICU stay: calculated by (admission date - discharge date * Weaning success rate

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Key information

Age range

40 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Ventilator-associated pneumonia (VAP) represents a significant sub-set of (HAP) remains the most frequent intensive care unit (ICU)-acquired infection its incidence ranges from 9% to 27% of ventilated patients ,VAP is associated with an increased length of stay, mortality and health care costs, Pneumonia can result in chest wall stiffness, decreased mobility, limiting the range of motion during breathing and decreased lung compliance and impaired respiratory function , Rib mobilization: is an articular , non-invasive, passive technique that can be useful with acutely ill, hospitalized patients emphasizes the placement of a repetitive force to increase the range of motion of the posterior rib articulations and chest wall , lessening somatic dysfunction of the spine, stretches myofascial structures and improve respiratory mechanics So, this study will be conducted to distinguish between effect of rib mobilization and routine chest physiotherapy on weaning parameters among intubated pneumonic patients on mechanical vent.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient's age ranged from 40- 50 years old from both genders.
  • Diagnosed with pneumonia and need invasive mechanical ventilation support.
  • Stable oxygen saturation (SpO2 more than 85, (FiO2) 0.6 or less, PEEP less than 10 Cm H2O).
  • mean arterial pressure > 75 mmHg and urine output > 1 mL/kg/h;
  • Patients with Glasgow coma scale (GCS) > 8T
  • Unconscious and semi-conscious patients. -

Exclusion criteria

  • Unstable hemodynamics
  • Unstable neurological problems e.g. (epileptic seizures -hyperthermia).
  • Unstable chest wall e.g. (multiple rib or vertebral fractures)
  • Increase intracranial pressure (>20 mmHg for >5 min).
  • Undrained pneumothorax, recent pulmonary surgery

Treatment and study plan

rib mobilization technique

Other

rib mobilization technique The patient in experimental group will be relaxed in semi- fowler position while connected to mechanical ventilator, therapist will seat at the patient "side, his fingers pads are placed at the position of the patient's rib angles , pulling upward and the lateral position the position is held while wait for the soft tissues to release this take from 15 seconds .Release of the diaphragm through manual contact with hypothenar region of therapist thumb inferior laterally xiphoid process and rest along Antero lateral costal margin below rib7 during exhalation the therapist thumb give pressure posteriorly repeat this steps for 3 to5 respiratory cycle • routine chest physiotherapy percussion on chest wall its frequency should be 3-7 beats per sec. vibration applying a light pressure with hand on affected segment for about 5 min modified postural drainage R. and L. side. U&L limb passive ex. for R.10 x3 set

.this program for 30 minutes once daily for ten days

routine chest physiotherapy

Other

routine chest physiotherapy the patient will be laid in half supine position connected to a ventilator applying

  • percussion on chest wall its frequency should be 3-7 beats per second or 180-420 beats per minute
  • vibration applying a light pressure with flattened hand on affected segment for about 5 minutes
  • modified postural drainage (right and left sidling 10 min for each side
  • upper and lower limb exercise for 4 limbs (3 sets and each set has 10 repetition
  • this program for 30 minutes once daily
  • for 10 consecutive days

Primary outcomes

  1. Arterial blood gases

    Time frame: at least 10 consecutive days

    • Arterial blood gases (ABG): (PH -PaO2 - PaCO2)
    • PaO2/FiO2 ratio (P/F): One element of predicting successful weaning from mechanical ventilation is PaO2/FiO2 > 200
  2. Respiratory rate (RR)

    Time frame: at least 10 consecutive days

    It will be measured using a mechanical ventilator.

  3. Tidal volume (TV)

    Time frame: at least 10 consecutive days

    It will be measured using a mechanical ventilator.

Secondary outcomes

  1. Length of hospital stay

    Time frame: at least 10 consecutive days

    ;• Length of stay in intensive care unite can be defined as the number of days that an in-patient will remain in ICU during a single admission event, is calculated by subtracting the admission date (ADATE) from the discharge date (DDATE)

Study contacts

Contact information is provided by the study sponsor or research team.

. Shymaa Mohamed Ali, lecturer

CONTACT

[email protected]

01144242511

hoda gaber el said, master

CONTACT

[email protected]

01100272020

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Feb 19, 2025
Registry last updated
Jul 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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