Skip to main content
OpenTrials
Completed

NCT Number: NCT06708325

Effect of Resistance Exercise on Physical and Psychological Factors

Physical inactivity is a key risk factor for cardiovascular and metabolic disorders, negatively affecting emotional well-being by increasing psychological distress and reducing mental health. This study aimed to evaluate the impact of a resistance-based physical activity program on physical and psychological outcomes in physically inactive adults.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Healthy Behavior Behavioral Symptoms Depression Physically Inactive

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Physiotherapy and Rehabilitation, Faculty of Medicine, Tekirdağ Namık Kemal University, Tekirdağ, Turkey,

Tekirdağ, Turkey (Türkiye)

About this study

Background/Objectives: Sedentary behavior is a prevalent risk factor contributing to the development and progression of cardiovascular and metabolic diseases. Additionally, physical inactivity has been linked to diminished emotional well-being, characterized by elevated levels of psychological distress and compromised mental health. The present study was designed to investigate the effects of a resistance-focused physical activity intervention on both physical and psychological health outcomes in adults with chronically low levels of physical activity. A randomized controlled trial design was employed. The participant comprised 32 adults (mean age = 46.61 ± 7.33 years) included in the study. These individuals were randomly allocated to either a resistance exercise group (EG, n = 15) or a control group (CG, n = 17). Comprehensive assessments were conducted at baseline and following the 12-week intervention. These assessments included evaluations of muscle strength (knee flexors, knee extensors, ankle dorsiflexors, plantar flexors, and core isometric strength), static and dynamic balance, proprioception, and functional movement capacity (as measured by the Functional Movement Screen (FMS)). Participants' psychological states were quantified using the Depression, Anxiety, and Stress Scale-21 (DASS-21). The EG participated in a supervised resistance training program 3 days per week for 12 weeks, with each session lasting approximately 55-60 minutes. Conversely, the CG did not engage in any structured exercise program and were advised to maintain their customary lifestyle habits throughout the study duration.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged between 40-60 years
  • Physically independent
  • Not having cardiac, orthopedic, or musculoskeletal dysfunctions
  • Not participating in regular physical activity more than once a week for the last 5 months before the beginning of the study

Exclusion criteria

  • Chronic ankle instability
  • Lower extremity musculoskeletal injury in the previous 6 months
  • Undergoing hormonal replacement therapy
  • Having uncontrolled diabetes
  • Having uncontrolled hypertension
  • Histroy of cardiovascular disease

Treatment and study plan

Resistance Training Program

Other

The 12-week resistance training program consisted of three supervised sessions per week, each lasting approximately 55-60 minutes. Sessions were structured as follows: 5-7 minute dynamic warm-up, 35-40 minutes of resistance training, and 4-5 minutes of stretching for active recovery.Participants were paired based on similar strength fitness levels and progressed according to the principle of periodized progressive overload. Training was delivered using a circuit protocol with 2-3 sets per exercise. The initial 4-week phase included 2 sets per exercise, with 8-20 repetitions and 1-2 minutes rest between sets. .The program incorporated functional exercises targeting the lower extremities, core, and upper extremities, utilizing equipment such as resistance bands, medicine balls, jump ropes, dumbbells, bars, and stability balls. Participants performed exercises in a circuit sequence, with the intensity, number of sets, and repetitions

Primary outcomes

  1. Depression

    Time frame: From enrollment to the end of treatment at 12 weeks

    The Depression, Anxiety, Stress Scale-21 (DASS-21) is a widely used self-report tool designed to measure depression, anxiety, and stress levels in participants. It consists of 21 items divided into three subscales:

    • Depression (e.g., feelings of sadness, lack of motivation)
    • Anxiety (e.g., nervousness, fearfulness)
    • Stress (e.g., tension, irritability)

    Each item is scored on a 4-point Likert scale, with the following options:

    • 0 = Did not apply to me at all
    • 1 = Applied to me to some degree, or some of the time
    • 2 = Applied to me to a considerable degree, or a good part of the time
    • 3 = Applied to me very much, or most of the time

    For each subscale, the scores range from 0 to 42 after adjustment.

  2. Functional Movement Screen Test Protocol

    Time frame: From enrollment to the end of treatment at 12 weeks

    a standardized assessment tool designed to evaluate fundamental movement patterns, identify asymmetries and weaknesses, and predict injury risk. The FMS consists of 7 movements: deep squat, hurdle step, in-line lunge, shoulder mobility, active straight leg raise, trunk stability push-up, and rotational stability.Each movement is scored on a 0-3 scale, with 3 indicating optimal performance. The maximum total score is 21.

  3. Balance

    Time frame: From enrollment to the end of treatment at 12 weeks

    Balance was assessed using the Sensbalance MiniBoard (Sensamove®, Utrecht, The Netherlands), a movable platform that provides an interactive challenge to balance control. Participants performed two tasks, each completed twice and held for 30 seconds

  4. Strength tests

    Time frame: From enrollment to the end of treatment at 12 weeks

    Lafayette Manual Muscle Test System (Model 01165) was used to determine isometric muscle strength. The Lafayette Manual Muscle Tester (MMT) system is an ergonomic handheld device used to objectively measure muscle strength.

Sponsors and collaborators

Lead sponsor

Monira Aldhahi

Other

Collaborators

  • Namik Kemal University

Registry information

Official study title

Effects of Resistance Exercise-based Physical Activity Programme on Physical and Psychological Factors in Inactive Adults

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Nov 27, 2024
Registry last updated
Dec 2, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.