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NCT Number: NCT07295184

Effect of Rebound Pain on Postoperative Intensive Care Delirium in Patients Undergoing Hip Surgery With Peripheral Nerve Block

Postoperative delirium is a significant and commonly encountered complication in patients undergoing hip surgery, particularly among the elderly. Postoperative delirium is associated with serious consequences, including prolonged intensive care unit stay, increased complication rates, higher mortality risk, and rising healthcare costs.

The incidence of Postoperative delirium after hip fracture surgery has been reported to range between 13% and 55.9%, indicating a substantial clinical burden.

Effective postoperative pain control is critical not only for maintaining quality of life but also for preserving cognitive well-being. In this context, peripheral nerve blocks are frequently used for pain management following hip surgery.

Recruiting

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Konya City Hospital

Konya, Karatay, 42100, Turkey (Türkiye)

Location status: Recruiting

Location contact

hasan şenay, MD

CONTACT

[email protected]

+905055078822

About this study

Postoperative delirium is a significant and commonly encountered complication in patients undergoing hip surgery, particularly among the elderly. Postoperative delirium is associated with serious consequences, including prolonged intensive care unit stay, increased complication rates, higher mortality risk, and rising healthcare costs.

The incidence of Postoperative delirium after hip fracture surgery has been reported to range between 13% and 55.9%, indicating a substantial clinical burden.

Effective postoperative pain control is critical not only for maintaining quality of life but also for preserving cognitive well-being. In this context, peripheral nerve blocks are frequently used for pain management following hip surgery.

In recent years, the Pericapsular Nerve Group block and the supra-inguinal fascia iliaca block have gained attention as regional anesthesia techniques that provide effective analgesia by targeting the nerve branches innervating the anterior capsule of the hip joint.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18-80
  • ASA I-III risk groups
  • Undergoing elective hip surgery

Exclusion criteria

  • Preoperative history of delirium, dementia, or major neurological disease
  • Present cognitive impairment or severe hearing or visual impairment that could affect pain assessment
  • Development of mechanical ventilation requirement in the intensive care unit; Need for bilateral hip surgery
  • Failure to provide meaningful analgesia after block application due to surgical pain outside the scope of the block
  • Patient's inability to complete the pain diary during postoperative follow-up;
  • Urgent hip surgery
  • Voluntary failure to give consent or request to withdraw from the study.

Treatment and study plan

Peripheral nerve block applied

Other

Pericapsular Nerve Group block and the supra-inguinal fascia iliaca block applied

Only multimodal analgesia applied

Other

Postoperative analgesia (paracetamol 1000 mg intravenously every 8 hours and celecoxib 200 mg orally every 12 hours)

Primary outcomes

  1. Incidence of delirium

    Time frame: 72 hours

    The incidence of delirium will be evaluated in the first 72 hours postoperatively in the intensive care unit.

Study contacts

Contact information is provided by the study sponsor or research team.

Hasan SENAY, M.D.

CONTACT

[email protected]

05055078822

Sponsors and collaborators

Lead sponsor

Konya City Hospital

Other

Registry information

Official study title

Effect of Rebound Pain on Postoperative Intensive Care Delirium in Patients Undergoing Hip Surgery With Peripheral Nerve Block: A Prospective Observational Study

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Dec 19, 2025
Registry last updated
May 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.