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Completed

NCT Number: NCT02424331

Effect of Pursed Lips Breathing on Chest Wall, Mobility Diaphragmatic and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease

This study aimed to evaluate the acute effect of PLB technique on diaphragmatic mobility, the kinematics of the thoracoabdominal complex analysis of lung volumes and exercise tolerance in patients with Chronic Obstructive Pulmonary Disease (COPD). This is a study randomized cross-over clinical trial and blind, in subjects with Chronic Obstructive Pulmonary Disease (COPD) according to criteria of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) (FEV1 / FVC <0.7 and FEV1 <80% predicted) selected at the Clinical Hospital of the Federal University of Pernambuco (UFPE) and Otavio de Freitas General Hospital (HGOF). The investigators recruited 13 patients COPD (according to previous sample calculation) aged between 40 and 80 years, of both sexes. The first day was held evaluation of lung function, respiratory muscle strength, body composition, dyspnea index and functional capacity. On the second day was held evaluation of thoracoabdominal complex kinematics by plethysmography Optoelectronics (OEP) with Quiet Breathing (QB) or pursed-lips breathing (PLB). Lung volumes with 2 minutes with QB and 6 minutes PLB or only 6 minutes by QB as randomization were observed. Before and after performing the requested breathing pattern diaphragmatic mobility was observed by Ultrasonography (US) and requested the patient an Inspiratory Capacity maneuver (IC). The evaluator who performed the ultrasound was blinded as to the beginning of the breathing pattern of order performed by the patient.

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Key information

Age range

40 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Clinical Hospital

Recife, Pernambuco, Brazil

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • COPD diagnosis with stage II-IV (GOLD),
  • Stable clinical condition (no exacerbation or hospital admission in the last four weeks preceding the study)
  • Absence of other disease that may potentially contribute to dyspnea (heart disease, congestive heart failure, neuromuscular diseases, severe postural changes)

Exclusion criteria

  • BMI> 30 kg / m2
  • Musculoskeletal limitations
  • Use of oxygen therapy
  • Extreme discomfort during the procedure application

Treatment and study plan

Pursed Lips Breathing

Other

Pursed Lips Breathing for six minutes.

Quiet Breathing

Other

Primary outcomes

  1. Chest wall (Analysis of lung volumes)

    Time frame: One day during eight minutes

    (L) by plethysmography optoelectronics.

  2. Mobility diaphragmatic (mobility diaphragmatic (mm) by Ultrassonography)

    Time frame: One day, before and after eight minutes of pursed lips breathing

    Analysis of mobility diaphragmatic (mm) by Ultrassonography.

  3. Exercise tolerance (Glittre AVD-Test)

    Time frame: One day, for six minutes approximately. The test will be repeated after 20 minutes of rest.

    Analysis by Glittre AVD-Test (capacity functional test) observing the test execution time (s).

Secondary outcomes

  1. Dyspnea (Borg and MRC Scale)

    Time frame: One day, before and after implementation of Glittre-ADL Test

    Assessed by Borg and MRC Scale (Medical Research Council).

Sponsors and collaborators

Lead sponsor

Universidade Federal de Pernambuco

Other

Registry information

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Apr 23, 2015
Registry last updated
Apr 23, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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