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Completed

NCT Number: NCT04710771

Effect of Prone Positioning in Patients With COVID-19

COVID-19 is affecting the people around the world and the infected individuals' may either stay asymptomatic or present to hospitals with severe distress and life threatening symptoms. The objective of the study is to investigate role of Prone positioning and alternate nostril breathing in patients with Covid-19.

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Key information

Conditions

Covid19 COVID-19 Coronaviridae Infections Coronavirus Infections Infections Lung Diseases Nidovirales Infections Pneumonia Pneumonia, Viral RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Age range

40 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

DHQ Hospital

Faisalabad, Punjab Province, 38000, Pakistan

About this study

In this quasi experimental study, 30 patients aged 40-80 years of either gender with a confirmed diagnosis of COVID-19 receiving supplemental oxygen were recruited from DHQ Hospital Faisalabad. patients were grouped into two A & B. We collected baseline data on demographics and anthropometrics. After baseline data collection, all the patients were helped into the prone position, which was maintained for a minimum duration of three hours. After that patients in group B performed alternate nostril breathing for 10 minutes with help of physiotherapist. Clinical data were re-collected on 3rd day of intervention one hour after returning to the supine position in group A and after alternate nostril breathing in group B. The main study outcome was the variation in oxygenation (partial pressure of oxygen [PaO2]/ fractional concentration of oxygen in inspired air [FiO2]) between baseline and resupination, and General psychological state through GAD-7 General anxiety disorder questionnaire.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age: 40-80 Gender: Both GCS score:15

Exclusion criteria

  • COPD Intubated ARDS Smoker Neurological Disorder

Treatment and study plan

Prone Lying Position

Other

patient lies on his/ her stomach facing floor.

Other names: Positioning

Alternate Nostril Breathing

Other

patient inspires with one nostril at a time, right or left one by one and expires by mouth.

Other names: breathing technique

Primary outcomes

  1. PaO2

    Time frame: Change in score before the intervention on 1st day of intervention and on 3rd day one hour after the intervention.

    partial pressure of oxygen.

  2. FiO2

    Time frame: Change in score before the intervention on 1st day of intervention and on 3rd day one hour after the intervention.

    Fractional concentration of oxygen in inspired air [FiO2])

  3. General Anxiety Disorder-7 Score

    Time frame: Change in score before the intervention on 1st day of intervention and on 3rd day one hour after the intervention.

    general anxiety disorder-7 score ranges from 0-21, out of which 0-4 means minimal anxiety, 5-9 stands for mild anxiety, 10-14 for moderate and 15-21 for severe anxiety.

Sponsors and collaborators

Lead sponsor

Sialkott College of Physical Therapy

Other

Registry information

Official study title

Effect of Prone Positioning and Alternate Nostril Breathing Technique in Patients With COVID-19: A Quasi Experimental Study.

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Jan 15, 2021
Registry last updated
May 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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