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Completed

NCT Number: NCT03151213

Effect of Pregabalin on the Postoperative Analgesia in RFA of Focal Lesions in the Liver

The study aimed to investigate the preemptive analgesia efficacy of of preemptive pregabalin for the postoperative pain management after radiofrequency ablation (RFA) of liver cancer.

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Key information

Conditions

Hepatocellular Cancer Digestive System Diseases Digestive System Neoplasms Liver Diseases Liver Neoplasms Neoplasms Neoplasms by Site

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Tanta university - faculty of medicine

Cairo, Elgharbia, Egypt

About this study

Our data will investigate if preemptive administration of pregabalin will have a role in reducing postoperative pain after radiofrequency ablation (RFA) of liver cancer.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • HCC patients, Child A, B, scheduled for Radiofrequency ablation of HCC.

Exclusion criteria

  • Encephalopathy, Renal impairment

Treatment and study plan

Pregabalin 150mg

Drug

Pregabalin 150mg before RFA of liver cancer

Other names: pregab

Placebo

Other

Placebo before RFA of liver cancer

Primary outcomes

  1. visual analogue pain scale (VAS Pain) post operatively

    Time frame: 2 weeks

    Amplitude of pain postoperatively

Sponsors and collaborators

Lead sponsor

Sherief Abd-Elsalam

Other

Registry information

Official study title

Effect of Preoperative Administration of Oral Pregabalin on the Postoperative Analgesia in Patients Scheduled for Radiofrequency Ablationof Focal Lesions in the Liver

Acronym: pregabalin

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
May 12, 2017
Registry last updated
Mar 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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