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Completed

NCT Number: NCT05638048

Effect of Precise Grip Strength Training on PICC Catheter-Related Thrombosis in Cancer Patients

In this study, color Doppler ultrasound diagnostic instrument and electronic grip device were used to determine the best grip strength of patients with tumor PICC catheterization, formulate precise and standardized grip strength training guidance for them, provide personalized functional exercise health education, and observe the impact of precise grip strength training guidance on Peripheral central venous catheter-associated thrombosis. To provide a reference for clinical prevention of Peripheral central venous catheter-associated thrombosis in the future.

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Key information

Conditions

Lung Cancer Breast Cancer Breast Diseases Breast Neoplasms Colon Cancer Colonic Diseases Colonic Neoplasms Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Liver Cancer Liver Diseases Liver Neoplasms Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Rectal Cancer Rectal Diseases Rectal Neoplasms Respiratory Tract Diseases Respiratory Tract Neoplasms Skin Diseases Skin and Connective Tissue Diseases Stomach Cancer Stomach Diseases Stomach Neoplasms Thoracic Neoplasms

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Qianfoshan Hospital

Jinan, Shandong, 250000, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Cancer patients undergoing chemotherapy throughout their treatment in our hospital
  • Patients with PICC implanted for the first time and maintained at our hospital;
  • Age 18-60 years;
  • Normal cognitive function;
  • the clenching movement is barrier-free;
  • The material and performance of PICC catheter are silicone three-way valve catheter;
  • Catheter placement under the guidance of portable color Doppler ultrasound diagnostic instrument;
  • Voluntarily participate and sign the informed consent form.

Exclusion criteria

  • Patients treated with combined radiotherapy;
  • Patients with coagulation dysfunction;
  • Patients who need to use anticoagulant drugs due to underlying diseases;
  • Puncture times more than 1 time;
  • The blood flow velocity of catheterization vessel in calm state was less than 4.78cm/s.

Treatment and study plan

Precision grip training

Behavioral

First determine patients for holding the ball movement should reach the effective blood flow velocity and best duration - relaxation, and USES the electronic grips and color doppler ultrasonic diagnostic apparatus, for individual patients to choose the best grip the efforts and training, to form the best grip the training plan, and observe the scheme for Peripheral central venous catheter-associated thrombosis prevention effect.

Use maximum strength grip training

Behavioral

Patients were routinely implanted with PICC, and on the basis of health education in the control group, the best continuous-relaxation time, frequency and maximum grip strength of patients were used for grip strength training.

Health education on routine grip strength training

Behavioral

Patients were routinely implanted with PICC and received routine health education. The content of health education included face-to-face language explanation of the whole process of catheter knowledge, issuing catheter maintenance manual, issuing ordinary grip ball and telling how to use it, and follow-up.

Primary outcomes

  1. Incidence of Peripheral central venous catheter-associated thrombosis in patients with PICC tube

    Time frame: 8 weeks

    Before catheterization, 24 hours after catheterization, and weekly maintenance, color Doppler ultrasound diagnostic instrument was used to diagnose venous thrombosis (including asymptomatic thrombosis) and its classification. The patients were observed for 8 weeks.

Secondary outcomes

  1. Hemodynamic changes of the patient

    Time frame: 8 weeks

    During weekly maintenance, color Doppler ultrasound was used to measure the blood velocity of the arm axillary vein on the side of the catheter, and the maximum blood velocity (Vmax, cm/s) was recorded.

  2. Analysis of the influencing factors of Peripheral central venous catheter-associated thrombosis formation

    Time frame: 8 weeks

    By investigating the baseline data of patients, the related factors affecting the formation of PICC-CRT in patients with tumor tube in the baseline data of the same group were analyzed and compared.

  3. Patients' satisfaction with health education after PICC catheterization

    Time frame: 8 weeks

    At the end of the intervention, the patients' attitude towards PICC catheterization health education questionnaire (self-made) was distributed to the study subjects, and the satisfaction of the study subjects with the health education after PICC catheterization was learned through the questionnaire.

Sponsors and collaborators

Lead sponsor

Junyan Zhao

Other

Registry information

Important dates

Study start
2022
Primary completion
2022
Study completion
2023
First posted
Dec 6, 2022
Registry last updated
Feb 3, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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