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Completed

NCT Number: NCT04626180

EFFECT OF PRE EXTUBATION MANUAL HYPERINFLATION TECHNIQUE VS REGULAR EXTUBATION AFTER STERNOTOMY

Post operative pulmonary complication (PPC) is one of the cause of mortality and morbidity after sternotomy. There is no accessible confirmation which shows the impact of Pre Extubation Manual Hyperinflation method with Regular Extubation procedure. After sternotomy manual hyperinflation technique is not taken during extubation. The objective of the study was to determine the effect of Pre Extubation Manual Hyperinflation technique VS regular Extubation technique on vitals and respiratory parameters in patients after Sternotomy.

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Key information

Conditions

Sternotomy

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bahria International Hospital

Rawalpindi, Punjab Province, 46000, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 40 to 60
  • Patient undergone surgery (sternotomy)
  • Elective intubated (ETT orally)
  • Ventilated more than 3 hours -

Exclusion criteria

  • Patient with any neurological issue (mentally disturbed) who cannot understand the command
  • Complicated extubation
  • Pulmonary pathology where lung hyperinflation was contra-indicated (e.g. acute respiratory distress syndrome, undrained pneumothorax or exacerbation of chronic obstructive pulmonary disease and acute pulmonary edema.
  • Raised intracranial pressure
  • Redo or reopen. -

Treatment and study plan

extubation

Procedure

Extubation is the removal of an endotracheal tube (ETT), which is the last step in liberating a patient from the mechanical ventilator.

Manual Hyperinflation

Procedure

Providing a larger tidal volume than baseline tidal volume to the patient and using a tidal volume which is 50% greater than that delivered by the ventilator

Primary outcomes

  1. Peak expiratory flow rate

    Time frame: 1 day

  2. Blood pH

    Time frame: 1 day

  3. Blood pO2

    Time frame: 1 day

  4. Blood pCO2

    Time frame: 1 day

  5. Blood pHCO3

    Time frame: 1 day

  6. Pulse rate

    Time frame: 1 day

  7. Oxygen saturation

    Time frame: 1 day

  8. Forced expiratory volume

    Time frame: 1 day

  9. Forced vital capacity

    Time frame: 1 day

Sponsors and collaborators

Lead sponsor

Foundation University Islamabad

Other

Registry information

Official study title

Effects of Pre-extubation Manual Hyper Inflation in Comparison to Regular Extubation Following Sternotomy.

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Nov 12, 2020
Registry last updated
Nov 12, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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