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Completed

NCT Number: NCT01436812

Effect of Positive End Expiratory Pressure (PEEP) on Cerebral Oxymetry During Laparoscopy

The investigators hypothesized that positive end expiratory pressure (PEEP) would increase the regional oxygen saturation (rSO2).

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Key information

Conditions

Cerebral Ischemia Brain Diseases Brain Ischemia Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Vascular Diseases

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Gachon University Gil Hospital

Incheon, South Korea

About this study

The investigators hypothesized that PEEP would increase the rSO2 during laparoscopic surgery by improving oxygenation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA PS I or II adult patient undergoing laparoscopic low anterior resection with Trendelenburg position

Exclusion criteria

  • Patients with history of cerebrovascular disease, coronary occlusive disease and/or obesity (body mass index > 30) were excluded from this study.

Treatment and study plan

zero end-expiratory pressure

Procedure

positive end expiratory pressure 0 cm H2O during peumoperitoneum

Other names: ZEEP

Positive end expiratory pressure

Procedure

PEEP 0 cmH2O

Other names: ZEEP

Primary outcomes

  1. cerebral ischemia

    Time frame: change from baseline in rSO2 at every events

    induction 10 min, Pneumoperitoneum 20 min, after PEEP apply 40 min, time of operation ending cerebral oxymetry, cerebral perfusion pressure record

Sponsors and collaborators

Lead sponsor

Gachon University Gil Medical Center

Other

Registry information

Official study title

International Reveiw Board of Gachon Univerity Gil Hospital

Important dates

Study start
2011
Primary completion
2012
Study completion
2013
First posted
Sep 20, 2011
Registry last updated
Aug 12, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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