Skip to main content
OpenTrials
Completed

NCT Number: NCT01826955

Effect of Pneumoperitoneum on Cognitive Function and Regional Cerebral Oxygen Saturation

The investigators hypothesized that the pneumoperitoneum with reverse Trendelenburg position could alter the rSO2 and early postoperative cognitive function.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Pneumoperitoneum Digestive System Diseases Peritoneal Diseases

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Gachon University Gil Medical Center

Incheon, South Korea

About this study

Laparoscopic gastrectomy requires a reverse-Trendelenburg position and prolonged pneumoperitoneum and it could cause significant changes in cerebral homeostasis and lead to cognitive dysfunction. We compared changes in haemodynamic variables, regional cerebral oxygen saturation, and early postoperative cognitive function in patients undergoing laparoscopic gastrectomy in the reverse Trendelenburg position with those patients that underwent conventional open gastrectomy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA class I or II, aged 20 to 70 yrs

Exclusion criteria

  • Patients with morbid obesity (body mass index > 30 kg/m2) or a history of cerebrovascular or respiratory disease were excluded.

Treatment and study plan

Primary outcomes

  1. MMSE

    Time frame: 5days after end of surgery

    5 days after operation MMSE (mini-mental status exam)was recorded

Sponsors and collaborators

Lead sponsor

Gachon University Gil Medical Center

Other

Registry information

Official study title

Effect of Pneumoperitoneum on Cognitive Function and Regional Cerebral Oxygen

Acronym: rSO2pneumo

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Apr 9, 2013
Registry last updated
Dec 24, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.