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NCT Number: NCT07728578

Effect of Pilates Training Versus High Intensity Interval Training on Cardiorespiratory Fitness in Asthmatic Patients

To compare the effect of Pilates Training Versus High Intensity Interval Training on Cardiorespiratory Fitness in Asthmatic Patients.

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Key information

Conditions

Asthma Bronchial Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

30 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

out-patient clinic, faculty of physical therapy, Horus university

Damietta, Egypt

Location contact

Ghidaa Elmahdi Eldomiaty, Assistant lecturer

CONTACT

[email protected]

+20 10 22143737

About this study

Asthma is a widespread chronic inflammatory disease affecting over 300 million people globally, leading to approximately 461,000 deaths annually. Exercise, particularly Pilates and high-intensity interval training, is critical for improving cardiorespiratory fitness and can enhance the quality of life for asthma patients, who often face reduced physical fitness and comorbidities like depression. Pilates improves respiratory control and strengthens respiratory muscles, while high-intensity interval training enhances aerobic and anaerobic capacities, reduces inflammation, and improves maximal oxygen uptake (VO₂ max). This study aims to establish guidelines comparing the effects of Pilates and high-intensity interval training on cardiorespiratory fitness in asthmatic patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 51 patients diagnosed with a clinical diagnosis of asthma and a history of respiratory illness, aged between 30 and 40 years.
  • Medically stable and capable of performing physical exercise.
  • All participants provided written informed consent before enrollment.
  • body mass index 25.0 - 29.9 (overweight)
  • Patients with partially controlled asthma according to the Asthma Control Questionnaire (ACQ) from 0 to 1.5.

Exclusion criteria

  • Participants with musculoskeletal limitations, cardiovascular instability, or any contraindications to exercise were excluded.
  • Uncontrolled hypertension.
  • Cognitive impaired patients.
  • Severe Anemic patients.
  • Pregnancy.
  • Recent cardiothoracic surgery.

Treatment and study plan

Pilates exercises

Other

17 Patients will perform Pilates exercises 40-60 mins, three times per week, over 8weeks.

Pilates exercises include five movements: The Hundred, Single Leg Stretch, Side Kick, Toe Taps, and Leg Pull Front, all performed with structured breathing Patterns To Emphasize Respiratory Control And Core Stabilization

low-volume high-intensity interval training

Other

17 patients will engage in low-volume high-intensity interval training complemented by diaphragmatic breathing exercises. Each session begins with a 5-10 minute warm-up on a treadmill at 40% of heart rate reserve. The targeted heart rate during high-intensity interval training is set at 85-90% of heart rate reserve plus resting heart rate. Participants will complete 3-minute high-intensity interval training intervals at the specified intensity, alternating with 2 minutes of moderate-intensity recovery at 60-70% heart rate reserve. Total exercise duration is 25-30 minutes, concluding with a 5-minute cool-down at 30% heart rate reserve.

diaphragmatic breathing exercise.

Other

Breathing in slowly and deeply through the nose using the diaphragm with a minimum movement of the chest in a supine position with one hand placed on the chest and the other on the belly. During breathing, practitioners should be careful that chest remains as still as possible and stomach moves against the hand focusing on contracting the diaphragm. Generally, diaphragmatic breathing practitioners inhale and exhale for approximately six seconds, respectively

Primary outcomes

  1. assessment of maximum oxygen consumption

    Time frame: At baseline and after 8 weeks

    Cardiopulmonary exercise testing is essential for evaluating patient symptoms, disease severity, prognosis, and therapy responses. It assesses the interaction of cardiovascular and pulmonary systems with other bodily systems. maximum oxygen consumption is calculated using the Bruce protocol via the Ergo Spiro Device. This protocol involves a multi-stage treadmill test, starting at a 10% grade and increasing speed and grade every three minutes until exhaustion. Subjects must refrain from eating, smoking, and consuming caffeine before testing, and avoid intense exercise leading up to the test.

Secondary outcomes

  1. assessment of Quality of Life

    Time frame: At baseline and after 8 weeks

    The Mini-Asthma Quality of Life Questionnaire is a shortened, 15-item version of the original questionnaire, designed to accurately assess the quality of life in asthmatic patients without consuming much time. It evaluates four domains: symptoms, activity limitation, emotional function, and environmental stimuli, based on the respondents' experiences over the past two weeks. it employs a 7-point Likert scale, where 7 indicates no impairment and 1 signifies significant impairment

  2. assessment of dyspnea

    Time frame: At baseline and after 8 weeks

    The Modified Borg Dyspnea Scale is a validated, numerical rating scale used to quantify the subjective perception of breathlessness during physical activity or exercise. The scale ranges from 0 to 10, where 0 indicates no breathlessness and 10 represents maximal or extremely severe breathlessness. Participants are instructed to rate their perceived level of dyspnea immediately after or during exercise, providing a simple, reliable, and clinically applicable measure of symptom intensity for monitoring exercise tolerance and evaluating treatment outcomes.

  3. assessment of asthma symptoms

    Time frame: At baseline and after 8 weeks

    Asthma Control Questionnaire (ACQ-6) is a six-item questionnaire designed to measure asthma symptoms. The questionnaire is scored by the mean of all items (0-6), with higher scores indicating poorer control.

Study contacts

Contact information is provided by the study sponsor or research team.

Ghidaa Elmahdi Eldomiaty, Assistant lecturer

CONTACT

[email protected]

+20 10 22143737

Sponsors and collaborators

Lead sponsor

Horus University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 27, 2026
Registry last updated
Jul 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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