Effect of Photobiomodulation on Pain Control After Placement of Elastomeric Spacers.

This randomized, controlled, double-blind, split-mouth clinical trial meets the criteria for designing a clinical study under the conditions of the SPIRIT Statement. The study was approved by the Committee for Ethics in Research (CEP) of the Universidad Católica del Uruguay. The participants who will be recruited are patients who are undergoing orthodontic treatment at the Orthodontic Clinic of the Specialization Course in Orthopedics and Orthodontics at the Catholic University of Uruguay in the city of Montevideo, Uruguay; those who require the installation of bands on the lower first permanent molars.

Any change or change will be reported and clarified to the CEP and informed in publications. A copy of the signed informed consent will be sent to the participant by email (completed in the TCLE). The project will be registered at www.clinicaltrial.gov There is no conflict of interest about any product used in the work and about any author involved in the studio. The data will be published and there will be no restriction on the inclusion of data for publication. All data will be available for your consultation, and all patients will have access to their medical records at any time they wish.

Inclusion criteria

• Patients will include:

• With the need to place bilateral orthodontic bands on the lower first molars.
• Age 13 to 30 years old.
• Both sexes.
• No comorbidities.
• Never used orthodontic appliances.
• Preserved surrounding spaces.
• Healthy permanent dentition with good hygiene.

Exclusion criteria

• Patients will be excluded:

• Who are taking drugs that affect bone metabolism and the inflammatory process (for example corticosteroids, bisphosphonates), who have used anti-inflammatory drugs or analgesics for less than 1 week since placing elastomeric separators.
• Present general pathologies (craniofacial anomalies) and local ones (dental anomalies) that affect the result of the movement of the teeth,
• Smokers, embarrassed, or breastfeeding women.
• Allergic to paracetamol®
• During the investigation, another different drug was used, which was made available by the investigators, and the patient was informed about this alteration.