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OpenTrials
Completed

NCT Number: NCT03308643

Effect of Oxytocin Infusion on Blood Loss During Abdominal Myomectomy

To evaluate the effects of oxytocin infusion during abdominal myomectomy.

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Key information

Conditions

Myomectomy Hemorrhage Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–50 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 4

Primary location

Kanuni Sultan Suleyman Egitim ve Arastırma Hastanesi

Istanbul, Turkey (Türkiye)

About this study

Myomectomy is indicated for symptomatic uterine fibroids. Fibroids have blood supply and 20% of the abdominal myomectomy cases might require blood transfusion because of the nature of the surgery. Oxytocin infusion is one of the intervention to decrease blood loss during myomectomy. To evaluate the effects and benefits of oxytocin infusion during abdominal myomectomy we decide to conduct this randomized study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18-50
  • Patients who are candidate for abdominal myomectomy

Exclusion criteria

  • History of previous myomectomy.
  • Suspected malignancy
  • Patients with preoperative anemia
  • Patients using hormonal treatments before the surgery.

Treatment and study plan

Oxytocin

Drug

Patients will receive intravenous oxytocin infusion just before the surgery after the induction of general anesthesia.

Saline

Other

Patients will receive intravenous normal saline infusion just before the surgery after the induction of general anesthesia.

Primary outcomes

  1. Blood loss during surgery

    Time frame: 2 hours

    estimated blood loss during the surgery measured by aspiration fluid.

Secondary outcomes

  1. Blood loss after abdominal myomectomy

    Time frame: 1 hour postoperatively

    change in Hematocrit Percentage (before and after the surgery)

Sponsors and collaborators

Lead sponsor

Kanuni Sultan Suleyman Training and Research Hospital

Other

Registry information

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Oct 12, 2017
Registry last updated
May 21, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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