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Completed

NCT Number: NCT00898170

Effect of Myoma Removal on Blood Pressure and Erythropoetin Level

The effect of myoma removal was studied on 28 patients with hypertension and myoma by holter monitoring and erythropoetin level check.

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Key information

Conditions

Myoma Cardiovascular Diseases Hypertension Neoplasms Neoplasms by Histologic Type Neoplasms, Connective and Soft Tissue Neoplasms, Muscle Tissue Vascular Diseases

Age range

22 year–55 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Cardiology Ward Shiraz University of Medical Sciences

Shiraz, Fars, 51318, Iran

About this study

Background:

Myoma is the most common gynecoid tumor and produces many vasoactive substances, which may be a cause for secondary hypertension. Early reports suggested the association of myoma and hypertension. We studied the effect of myoma removal on hypertension and erythropoietin level to evaluate this hypothesis.

Patients & Methods:

In this single centered prospective cohort study, in twenty eight patients who were candidates for myomectomy due to myoma, 24 hour holter monitoring of blood pressure and serum erythropoietin were checked before and 6 weeks after hysterectomy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • candidate for myoma removal by hysterectomy
  • operable
  • hysterectomy is indicated

Exclusion criteria

  • patient refusal
  • inoperable patients
  • other secondary cases of hypertension

Treatment and study plan

myoma removal

Procedure

surgical removal of myoma by hysterectomy

Primary outcomes

  1. 24 hour holter monitoring of blood pressure

    Time frame: 6 weeks

Secondary outcomes

  1. erythropoetin level

    Time frame: 6 weeks

Sponsors and collaborators

Lead sponsor

Shiraz University of Medical Sciences

Other

Registry information

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
May 12, 2009
Registry last updated
May 12, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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