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NCT Number: NCT06653543

Effect of Mulligan on Cervical Radiculopathy

The goal of this clinical trial is to investigate the effect of Mulligan mobilization with arm movement on nerve conduction velocity in patients with unilateral cervical radiculopathy. The main questions it aims to answer are :

1. Is there a statistical significant effect of mobilization with arm movement on NCV velocity in treatment of cervical radiculopathy ? 2. Is there a statistical significant effect of mobilization with arm movement on pain level in treatment of cervical radiculopathy ? 3. Is there a statistical significant effect of mobilization with arm movement on cervical ROM in treatment of cervical radiculopathy ? 4. Is there a statistical significant effect of mobilization with arm movement on neck disability level in treatment of cervical radiculopathy ?

The course of treatment involves 6 sessions over the course of 3 weeks participants will be divided into 2 groups : Control group : recieves only Conventional treatment Experimental group : recieves Conventional treatment and Mulligan mobilization with arm movement .

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Key information

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kafr El-Sheikh university

Kafr El-Sheikh Governorate, Kafr el-Sheikh Governorate, 33516, Egypt

Location status: Recruiting

Location contact

university

CONTACT

[email protected]

047 3109590

About this study

the aim of our study is to examine the effect of Mulligan mobilization with arm movement on cervical radiculopathy using nerve conduction studies , in addition to the original measures of previous studies (pain level, cervical ROM and neck disability scale) .

Delimitations :

Inclusion criteria

Individuals will be enrolled into the study if they are :

  • diagnosed with cervical radiculopathy .
  • Age group between 20-60 years
  • Unilateral radiating pain through the course of median nerve .
  • Subject having positive upper limb tension test (ULTT 1)
  • either gender male and female
  • Subjects who can understand the instructions and are willing to participate in the study.

Exclusion criteria

.

  • History of trauma, dislocation and subluxation of upper extremity
  • Rheumatoid Arthritis
  • Malignancy
  • Spinal canal stenosis .
  • Cervical instability/Spondylolisthesis
  • VBI (Vertebral-Basillar Insufficiency)
  • Referred pain in patients with cardiac ischemia
  • Cervical or thoracic spine surgeries
  • systemic causes like diabetic neuropathy.
  • recent fracture or surgery in and around the shoulder
  • carpal tunnel syndrome .
  • thoracic outlet syndrome .

Outcome measure would include:

A) The primary outcome measure will be NCV velocity, for the median nerve (latency, amplitude, Duration , F-wave and nerve conduction velocity of motor nerve action potentials and sensory nerve action potentials (SNAPs)) .

B) Secondary outcome measures will include:

  • Pain intensity, assessed using the Visual Analog Scale (VAS) .
  • Functional disability, evaluated using the Neck Disability Index (NDI) .
  • Cervical range of motion, measured using a CROM goniometer to assess flexion, extension, lateral flexion, and rotation.
  • The course of treatment involves 6 sessions over the course of 3 weeks .
  • pre-treatment for both groups :
  • affected nerve conduction velocity will be measured using nerve conduction study .
  • neck disability level will be measured using neck disability index .
  • cervical ROM measurement will be taken in all directions using CROM goniometer .
  • pain will be assessed using Visual analog scale .

participants will be divided into 2 groups :

Group A- Control group:

During each session : only Conventional treatment will be provided , includes : hot pack for 10 minutes, active ranges of motion (AROMs) with 3 sets of 10 repetitions and isometrics for each movement repeated 20 times with the hold of 6 to 10 seconds in each repetition.

Group B- Experimental group- Mulligan mobilization group:

  • During each session :
  • Conventional treatment will be provided .
  • Mulligan mobilization will be applied in the form of : sustained passive accessory joint mobilization to a specific spinal vertebra level while simultaneously guiding the patient through an active, pain-free movement pattern involving the affected limb :
  • Patient position : Sitting upright on chair
  • Therapist position : Standing behind the patient .
  • Hand placement : Approach the desired level of spinous process from medial aspect of the thumb of one hand, which may be reinforced by the index finger of the other hand.
  • Mobilization Pure transverse glide is performed from affected to unaffected side. While the glide is sustained, patient performs the offending movements (flexion/abduction/horizontal adduction/horizontal abduction)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • • diagnosed with cervical radiculopathy .
  • Age group between 20-60 years
  • Unilateral radiating pain through the course of median nerve .
  • Subject having positive upper limb tension test (ULTT 1)
  • either gender male and female
  • Subjects who can understand the instructions and are willing to participate in the study.

Exclusion criteria

  • • History of trauma, dislocation and subluxation of upper extremity
  • Rheumatoid Arthritis
  • Malignancy
  • Spinal canal stenosis .
  • Cervical instability/Spondylolisthesis
  • VBI (Vertebral-Basillar Insufficiency)
  • Referred pain in patients with cardiac ischemia
  • Cervical or thoracic spine surgeries .
  • systemic causes like diabetic neuropathy .
  • recent fracture or surgery in and around the shoulder .
  • carpal tunnel syndrome .
  • thoracic outlet syndrome .

Treatment and study plan

Mulligan mobilization with arm movement

Other

mulligan mobilization applied on cervical spine with arm movement

conventional therapy of cevical radiculopathy

Other

hot pack for 10 minutes, active ranges of motion (AROMs) with 3 sets of 10 repetitions and isometrics for each movement repeated 20 times with the hold of 6 to 10 seconds in each repetition

Primary outcomes

  1. median nerve conduction study

    Time frame: 2 weeks

    using nerve conduction studies to measure the median nerve (latency, amplitude, Duration , F-wave and nerve conduction velocity of motor nerve action potentials and sensory nerve action potentials ) .

Secondary outcomes

  1. cervical range of motion

    Time frame: 2 weeks

    using cervical CROM device to measure the cervical ROM in all 3 planes

  2. pain

    Time frame: 2 weeks

    using visual analogue scale for the pain intensity .. where no pain or discomfort(0) , while the severest pain (10) .. the more the pain , the more the points on the scale

  3. neck disability level

    Time frame: 2 weeks

    using neck disability index questionnaire consists of 10 items, where each item is scored on a scale of 0 to 5, with 0 indicating no disability and 5 indicating complete disability

    • The total score ranges from 0 to 50.
    • Higher scores indicate greater disability and impairment, while lower scores indicate less disability.

Study contacts

Contact information is provided by the study sponsor or research team.

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Effect of Mulligan Mobilization With Arm Movement on Nerve Conduction Velocity in Patients With Unilateral Cervical Radiculopathy

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Oct 22, 2024
Registry last updated
Apr 27, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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