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Completed

NCT Number: NCT01317251

Effect of Milk and Cheese on Fecal Fat Excretion and Blood Lipid

The aim is to study the effect of milk versus cheese on fecal fat excretion and blood lipids. To do this, a randomized crossover intervention study with 3 14-day periods (control diet, milk diet, cheese diet) will be conducted in 16 young males. Fasting blood samples will be collected before and after each period, and fecal samples will be collected for the last 5 days in each period.

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Key information

Conditions

Obesity Body Weight Dyslipidemias Hyperlipidemias Lipid Metabolism Disorders Metabolic Diseases Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–50 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Department of Human Nutrition, University of Copenhagen

Frederiksberg C, 1958, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy males
  • BMI 20-28 mg/m2

Exclusion criteria

  • Smoking
  • Medicine use
  • Dietary supplements
  • Lactose intolerance, milk allergy
  • Dislike of dairy products
  • Excessive physical activity (> 10h/wk)
  • Known chronic illnesses

Treatment and study plan

Dietary intervention (without dairy products)

Other

Control diet without dairy products

Dietary intervention (high milk content)

Other

Diet with a high content of milk (~1200 mg Ca/d from milk)

Dietary intervention (high cheese content)

Other

Diet with a high content of cheese (~1200 mg Ca/d from cheese)

Primary outcomes

  1. Fecal fat excretion

    Time frame: During day 10-14 in each period

    Total excretion of fecal fat (grams/day)avaraged over five days

Secondary outcomes

  1. Total, HDL and LDL cholesterol

    Time frame: Day 1 and 14 in each period

  2. Triglycerides

    Time frame: Day 1 and 14 in each period

  3. Appetite sensation

    Time frame: Assessed on day 1, 8 and 14 in each period

Sponsors and collaborators

Lead sponsor

University of Copenhagen

Other

Registry information

Acronym: MOFF

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Mar 17, 2011
Registry last updated
Sep 5, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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