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Completed

NCT Number: NCT01791400

Effect of Metoclopramide Versus Sumatriptan for Emergency Department Treatment of Migraine Headache

The purpose of this study is to determine which drug makes lower migraine headache

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Key information

Conditions

Migraine Disorders Brain Diseases Central Nervous System Diseases Headache Headache Disorders Headache Disorders, Primary Nervous System Diseases Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Al-zahra university hospital

Isfahan, Iran

About this study

There are different options to manage benign headache in emergency department.The investigators compared Intravenous metoclopramide with Subcutaneous sumatriptan to relieve pain in emergency department.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 20-60 years old and presented with acute headache similar to previous episodes,
  • with or without phonophobia,
  • photophobia,
  • vomiting or nausea.

Exclusion criteria

  • fever or neck stiffness,
  • altered mental state,
  • pregnancy,
  • recent trauma or seizure (within 24 hours),
  • focal neurological abnormality on physical examination,
  • allergy to metoclopramide,
  • hypertension,
  • cardiovascular diseases.

Also if the patients had taken a triptan or ergot during the last 24 hours were excluded from the study.

Treatment and study plan

metoclopramide, injection,20mg, one time

Drug

metoclopramide, intravenous injection,20mg, one time

Other names: plasil

Sumatriptan, injection, 6 mg, one time

Drug

Sumatriptan, subcutaneous injection, 6 mg, one time

Primary outcomes

  1. pain

    Time frame: at one hour after prescription

    determining pain in Metoclopramide versus sumatriptan groups

Sponsors and collaborators

Lead sponsor

Isfahan University of Medical Sciences

Other

Registry information

Official study title

Study of Effects of Metoclopramide Versus Sumatriptan on Migraine Headache

Important dates

Study start
2009
Primary completion
2010
Study completion
2010
First posted
Feb 15, 2013
Registry last updated
Feb 15, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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