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Completed

NCT Number: NCT06233955

Effect of Maitland Mobilization With Low Level Laser Therapy in Treatment of Patients With Knee Osteoarthritis

Background: Osteoarthritis is a common cause of chronic pain and disability in elderly people.

Objective: To evaluate the efficacy of low-level laser therapy (LLLT) in combination with Maitland mobilization and conventional physical therapy in patients with chronic knee osteoarthritis.

Design: Pre-test post-test randomized control trial.

Completed

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Key information

Conditions

Knee Osteoarthritis Arthritis Joint Diseases Musculoskeletal Diseases Osteoarthritis Osteoarthritis, Knee Rheumatic Diseases

Age range

50 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of physical therapy Cairo university

Cairo, Dokki, 02, Egypt

About this study

Knee OA is associated with pain and disability, high treatment costs, decreased productivity, and absence from work and thus has a substantial and growing burden on society Objective: To evaluate the efficacy of low-level laser therapy (LLLT) in combination with Maitland mobilization and conventional physical therapy in patients with chronic knee osteoarthritis.

Participants: Seventy five subjects of both genders with age range from 50 to 65 years, with proven bilateral knee OA diagnosed and referred by orthopaedist were recruited for the study and randomly assigned into three groups.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Subjects with proven bilateral Knee OA with age range 50- 65 years according to the American College of Rheumatology criteria.

2- Only patients with X-ray stages II and III osteoarthritis selected according to Kellgren & Lawrence classification system.

3- BMI equal to or less than 30 . 4- Patients with Knee pain lasted at least 6 months with intensity at least 3 on VAS scale in activities such as going up-and downstairs, sitting and squatting.

5- Patients with normal mental state. 6- Patients who are not participating in physical therapy in the recent 3 months.

.

Exclusion criteria

  • Patient with history of gout, infection, tumour, autoimmune diseases, trauma or other causes of knee pain or knee deformities.
  • Patient with neurologic dysfunction, or with history of chronic disease that may affect the study.
  • Patient with history of knee intra-articular injection in the past 6 months.

Treatment and study plan

Low Level Laser Therapy

Device

is a non-invasive light source treatment that generates a single wavelength of light. It emits no heat, sound, or vibration. It is also called photobiology or bio-stimulation

Other names: LLLT

Maitland mobilization technique

Other

is a process of examination; assessment and treatment of musculoskeletal disorders by manipulative physiotherapy where a chain of oscillatory joint mobilization grades based on the pathological limit of tissue are used

Primary outcomes

  1. Visual analogue scale

    Time frame: Four weeks

    Is a bidirectional 10 cm straight line with two labels, that is, "no pain" and "worst possible pain", located at either end of the line. Patients were instructed to draw a vertical mark on the line indicating their pain level where zero mean no pain and 10 means worst imaginable pain

  2. Pressure Algometer

    Time frame: Four weeks

    is a handheld pressure algometer that responds linearly to force application between 0 and 5 Kg and it has a 1-cm2 round rubber tip.

  3. Knee digital goniometry

    Time frame: Four weeks

    Baseline digital absolute + axis TM goniometer was used which consisted of one movable arm and one fixed arm and fulcrum

Secondary outcomes

  1. Knee injury and osteoarthritis outcome score short form

    Time frame: Four weeks

    consists of a seven items measure of physical function descended from the items of the function, daily living and function, sports and recreational activity subscales of the KOOS Item responses are coded from 0 to 4, none to extreme respectively. The questionnaire is scored by summing the raw response (range 0-28) and then using the nomogram so the raw score is converted to a true interval score (0-100) where zero means no difficulty and 100 means extreme difficulty

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2021
Primary completion
2023
Study completion
2023
First posted
Jan 31, 2024
Registry last updated
Jan 31, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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