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NCT Number: NCT06965426

Effect of Lutein, Zeaxanthin, and Meso-Zeaxanthin Supplementation on Skin Carotenoid Concentration: A Six-Month, Placebo-Controlled Crossover Study

To compare skin carotenoid scores over 12 weeks of individuals randomized to placebo or MacuHealth and comparing that to a 12 week crossover evaluation.

Recruiting

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Key information

Conditions

Macular Degenerative Disease Eye Diseases Macular Degeneration Retinal Degeneration Retinal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients 18-50 years old of any sex and any race.
  • Willing to comply with the protocol instructions.
  • Has read (or has had read to), understood, and signed an Informed Consent.

Exclusion criteria

  • Current Smoker
  • Pregnant, plan to become pregnant or breastfeeding
  • History of any non-controlled disease states including diabetes, cancer, heart diseases ETC (we need to confirm this with previous protocols) BMI greater than 30
  • Currently taking MacuHealth or similar supplements or previous use

Treatment and study plan

Lutein, Zeaxanthin, and Meso-Zeaxanthin Supplementation

Other

Lutein, Zeaxanthin, and Meso-Zeaxanthin Supplementation

Other names: MacuHealth

Primary outcomes

  1. Carotenoid concentration

    Time frame: 6 months

    Change in skin carotenoid concentration over supplementation vs. placebo exposure durations.

Study contacts

Contact information is provided by the study sponsor or research team.

Crystal Remington, OD

CONTACT

[email protected]

8165319100

Ryan Powell, OD

CONTACT

[email protected]

8165319100

Sponsors and collaborators

Lead sponsor

Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,

Other

Collaborators

  • MacuHealth

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
May 11, 2025
Registry last updated
Sep 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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