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OpenTrials
Completed

NCT Number: NCT06001424

Effect of Life Kinetik Training on Lower Limb Coordination in Ataxic Patients

Coordination is essential for the performance of most daily motor activities. Coordination problems are common in MS patients. One of the most commonly reported symptoms is dysmetria (limb ataxia). Ataxia is thought to occur in about 80% of MS patients. It leads to limitations in daily life activities. Aim of Study: to investigate the effect of life kinetik training on lower limb coordination in MS patients with ataxia.

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Key information

Conditions

Multiple Sclerosis Ataxia Autoimmune Diseases Autoimmune Diseases of the Nervous System Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Dyskinesias Immune System Diseases Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Physical Therapy

Giza, 11432, Egypt

About this study

Methods: Thirty remitting relapsing Multiple Sclerosis (RRMS) patients from both sexes with ataxic symptoms, will be recruited from multiple sclerosis specialized clinic in the Neurology department, Faculty of Medicine, Cairo University with EDSS score will be ranged from 2 to 4 and SARA score will be ranged from 1 to 10. Lower Extremity Motor Coordination Test (LEMOCOT) will be used to assess lower limb motor coordination. They will be randomly assigned into two equal groups; control group (GI) will receive selected physical therapy program and study group (GII) will receive same program of (GI) in addition to life kinetik training.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • MS from both sexes
  • Patients' age will be ranged from 20 to 45 years
  • Expanded disability scale (EDSS) score ranging from "two" to "four"

Exclusion criteria

  • Patients with Ataxia caused by other cause rather than MS
  • Patients with other neurological disease or orthopedic deformities may affect movement
  • Patients with cardiovascular and pulmonary diseases that make exercise unsafe
  • Patients with cognitive impairment or psychiatric disorders

Treatment and study plan

Physical Therapy

Other

Frenkel's exercises for lower limb, Proprioceptive neuromuscular facilitation for upper limb in the form of rhythmic stabilization

life kinetic exercises

Other

A multimodal training that combines coordinative, cognitive and visual tasks.

Primary outcomes

  1. Lower Extremity Motor Coordination Test (LEMOCOT)

    Time frame: at baseline

    test to assess lower limb coordination

  2. Lower Extremity Motor Coordination Test (LEMOCOT)

    Time frame: post intervention (after one month)

    test to assess lower limb coordination

Secondary outcomes

  1. Four Square Step Test (FSST)

    Time frame: at baseline

    test to assess dynamic balance

  2. Four Square Step Test (FSST)

    Time frame: post intervention (after one month)

    test to assess dynamic balance

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2018
Primary completion
2021
Study completion
2021
First posted
Aug 21, 2023
Registry last updated
Aug 21, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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