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Completed

NCT Number: NCT02826746

Effect of Intravenous Magnesium on Postoperative Sore Throat After Thyroidectomy

The primary purpose of this study is to investigate the effect of intravenous magnesium on postoperative throat pain after thyroidectomy.

The secondary purpose of this study is to investigate the effect of intravenous magnesium on total dose of fentanyl in recovery room after thyroidectomy.

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Key information

Conditions

Thyroid Neoplasms Endocrine Gland Neoplasms Endocrine System Diseases Head and Neck Neoplasms Neoplasms Neoplasms by Site Thyroid Diseases

Age range

20 year–85 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine

Suwon, Seoum, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Thyroidectomy

Exclusion criteria

  • Allergy to magnesium
  • Chronic pain
  • Chronic opioid use
  • Chronic NSAID use
  • Renal dysfunction
  • Liver dysfunction
  • Cardiac arrythmia
  • Seizure

Treatment and study plan

Magnesium sulfate

Drug

adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h

normal saline

Drug

the same bolus and infusion volumes of normal saline

Primary outcomes

  1. Throat pain

    Time frame: Up to 48 hours after surgery end

    pain assessment using visual analog scale

Secondary outcomes

  1. Fentanyl dose in recovery room

    Time frame: Up to 30 minutes after surgery end

Sponsors and collaborators

Lead sponsor

Ajou University School of Medicine

Other

Registry information

Important dates

Study start
2016
Primary completion
2019
Study completion
2019
First posted
Jul 11, 2016
Registry last updated
Apr 5, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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