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OpenTrials
Completed

NCT Number: NCT06304909

Effect of Intravenous Dexmedetomidine Versus Dexamethasone for Management of Repound Pain After Supraclavicular Brachial Plexus Block

Effect of intravenous dexmedetomidine versus dexamethasone for management of repound pain after supraclavicular brachial plexus block.

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Key information

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Marwa Mahmoud Rady

Asyut, Assiut Governorate, 1987, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients between 20_60 years old
  • Patients with ASA clinical status I/II
  • Patients scheduled for peripheral nerve block for upper extremity surgery

Exclusion criteria

  • 1) they refused to participate 2) had preexisting neuropathy of the surgical limb 3) hypersensitivity to amide anesthetic 4) significant pulmonary disease 5) coagulopathy 6) sepsis 7) infection at the block site 8) hypersensitivity to dexmedetomidine & dexamethasone

Treatment and study plan

Dexmedetomidine Injection

Drug

Dexmedetomidine group will receive 0.5 mcg/kg

Dexamethasone

Drug

Dexamethasone group will receive 8mg/kg

Saline

Drug

receive equivalent volume of saline 0.9%.

Primary outcomes

  1. The incidence of rebound pain.

    Time frame: 1year

    Rebound pain is defined as an increase from well-controlled to severe pain typically within 12_24 h of resolution of the nerve block.

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Mar 12, 2024
Registry last updated
Jun 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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