Effect of Intensive Nutritional Support in Subacute Stroke Patient

Inclusion criteria

• Acute first-ever stroke patients less than 7 days after onset

• more than 19 years old at stroke onset ③ stroke confirmed by brain CT or MRI

• body mass index (BMI) <25 before the comprehensive rehabilitation ⑤ Mini Nutritional Assessment < 12 before the comprehensive rehabilitation ⑥ Fugl-Meyer assessment < 85 at 7 days after stroke onset

Exclusion criteria

• Transient ischemic stroke

• Progressive or unstable stroke

• Pre-existing and active major neurological disease, e.g., spinal cord injury, Parkinson's disease, et al.

• Pre-existing and active (e.g., on chronic medication) major psychiatric disease, such as major depression, schizophrenia, bipolar disease or dementia ⑤ Advanced liver, kidney, cardiac, or pulmonary disease, e.g., advanced hepatocellular carcinoma, end-stage renal failure, et al.)

• A terminal medical diagnosis consistent with survival < 1 year

• Diabetes mellitus, Hyperlipidemia, Metabolic syndrome, Heart failure) ⑧ Pregnant or lactating women ⑨ Prohibited from taking medication (Omapone Peri 724mL or Winuf Peri 654mL)