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OpenTrials
Completed

NCT Number: NCT00184444

Effect of Increased Oxygenation in the Air During Endurance Training in Stable Angina Pectoris Patients

The study investigates whether endurance training breathing 100% oxygen gives a additional improvement of maximal oxygen uptake in stable Angina Pectoris patients, compared to training without extra oxygen supplementation. In addition work economy, stroke volume and cardiac perfusion is measured.

The hypothesis of the study is that increased oxygenation of the air increases performance, stroke volume, work economy and cardiac perfusion.

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Key information

Conditions

Angina Pectoris Cardiovascular Diseases Chest Pain Heart Diseases Hyperoxia Myocardial Ischemia Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Respiratory Vascular Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Norwegian University of Science and Technology

Trondheim, 7489, Norway

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • stable angina pectoris age 18-75

Exclusion criteria

  • unstable angina pectoris
  • Limitations to exercise other than coronary artery disease
  • Participants in other study interventions

Treatment and study plan

Hypoxic interval training

Behavioral

4 x 4 minutes interval training in hypoxic air, 3 times per week at 90-95% HR max

Normoxic interval training

Behavioral

4 x 4 minutes normoxic interval training, 3 times per week at 90-95% HR max

Primary outcomes

  1. maximal oxygen uptake

    Time frame: Baseline and post training

Secondary outcomes

  1. Cardiac perfusion

    Time frame: Baseline and post training

  2. work economy

    Time frame: Baseline and post training

  3. cardiac output

    Time frame: baseline and post training

Sponsors and collaborators

Lead sponsor

Norwegian University of Science and Technology

Other

Collaborators

  • Aarhus University Hospital

Registry information

Important dates

Study start
2004
Primary completion
2007
Study completion
2007
First posted
Sep 16, 2005
Registry last updated
Jul 20, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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