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OpenTrials
Completed

NCT Number: NCT01644838

Effect of Hyoscine and Promethazine on Labor Pain

It is always considered to shorten the duration of delivery without compromising the mother and fetus by obstetrics. Hyoscine and Promethazine are used widely in hospital and research is very limited, with conflicting results regarding the efficacy of these two drugs. So the investigators decided to compare of effect of hyoscine N-butyl bromide and Promethazine on length of active phase of the first stage of labor.

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Key information

Conditions

Labor Pain Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–35 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 2 / Phase 3

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-35 yrs,
  • primiparous,
  • having single fetus with cephalic presentation, gestational age 37-42 weeks,
  • having no medical diseases,
  • having no history of hospitalization due to psychological diseases,
  • having no addiction to cigarette,
  • having no complications during pregnancy such as hypertension,
  • BMI< 26

Exclusion criteria

  • bleeding
  • CPD
  • use of PG or Oxytocin
  • fetus distress

Treatment and study plan

Hyoscine

Drug

The samples were randomly allocated to inject of 20 mg of hyoscineIM in dilatation 3-5cm.

Promethazine

Drug

The samples were randomly allocated to inject of 25 mg of promethazine IM in dilatation 3-5cm.

Primary outcomes

  1. Effect of Hyoscine and Promethazine on labor pain

    Time frame: up to 9 months

Sponsors and collaborators

Lead sponsor

Mashhad University of Medical Sciences

Other

Registry information

Official study title

Principal Investigator

Important dates

Study start
2010
Primary completion
2011
Study completion
2011
First posted
Jul 19, 2012
Registry last updated
Jul 20, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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