Diego Serrano-Muñoz
Toledo, 45004, Spain
NCT Number: NCT02837458
The purpose of this study is to determine whether the transcutaneous application of unmodulated high frequency alternating currents could produce a quickly conduction block of peripheral nerve.
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Notify Me18 year–65 year
All sexes
Interventional
Not applicable
Toledo, 45004, Spain
In the last years several animal experimental studies have evidenced that high frequency unmodulated currents about 5 KHz can cause a peripheral nerve block. However electric currents with these high frequencies that are usually used for the treatment of pain in humans are interrupted or modulated (i.e. interferential currents).
It has show that the diameter of the nerve it is related with the frequency to produce the conduction block. For this reason we decided to applied 30KHz to observe the effects on pain in patients with whiplash and to compare versus sham stimulation.
Only one study has applied 5KHz on experimental pain and they have demonstrated changes in somatosensory thresholds.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
high-Frequency electrical stimulation over superficial radial nerve through the electrotherapy device Myomed 932. (Enraf-Nonius, Delft, Netherlands)
Sham transcutaneous electrical stimulation over superficial radial nerve through the electrotherapy device Myomed 932. (Enraf-Nonius, Delft, Netherlands)
Time frame: baseline at 0 min
The pressure pain threshold will be measured by a pressure algometer and will be expressed in Newton
Time frame: baseline at 0 min
The tactile threshold will be measured with Von Frey filaments and will be expressed in millinewton
Time frame: Baseline at 0 min
The muscle strength will be measured with a dynamometer and will be expressed in Newton
Time frame: Immediately after treatment at 30 min
The pressure pain threshold will be measured by a pressure algometer and will be expressed in Newton
Time frame: Immediately after treatment at 30 min
The tactile threshold will be measured with Von Frey filaments and will be expressed in millinewton
Time frame: Immediately after treatment at 30 min
The muscle strength will be measured with a dynamometer and will be expressed in Newton
Time frame: baseline at 0 min, immediately after treatment at 30 min
The pressure pain threshold will be measured by a pressure algometer and will be expressed in Newton
Time frame: baseline at 0 min, immediately after treatment at 30 min
The tactile threshold will be measured with Von Frey filaments and will be expressed in millinewton
Time frame: baseline at 0 min, immediately after treatment at 30 min
The muscle strength will be measured with a dynamometer and will be expressed in Newton
University of Castilla-La Mancha
Other
Application of High Frequency Electrical Currents: Effects on Mechanical Threshold, Tactile Threshold and Evoked Potentials in Healthy Subjects.
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