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OpenTrials
Completed

NCT Number: NCT01682343

Effect of High-calcium Intake on Appetite, Insulinemia and Incretins

The purpose of this study is to investigate the appetite, insulin and incretin hormone responses to a high-calcium meal.

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Key information

Conditions

Nutritional and Metabolic Diseases

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Northumbria University

Newcastle upon Tyne, Tyne on Wear, NE1 8ST, United Kingdom

About this study

Participants will be provided with control and high-calcium meals. Insulin, appetite, glucagon-like peptide-1 and glucose-dependent insulinotropic peptide responses will be assessed, along with rates of substrate oxidation.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • recreationally active
  • male

Exclusion criteria

  • food intolerances/allergies

Treatment and study plan

Calcium

Dietary Supplement

Milk-calcium supplement

Primary outcomes

  1. Subjective appetite ratings

    Time frame: 3 hour

    Subjective ratings of appetite assessed by visual analogue scales.

Secondary outcomes

  1. Serum insulin concentration

    Time frame: 2 hour

    2 hour area under the curve for serum insulin following breakfast consumption

  2. Plasma glucose-dependent insulinotropic peptide concentration

    Time frame: 2 hour

    2 hour area under the curve for plasma glucose-dependent insulinotropic peptide following breakfast consumption

  3. Plasma glucagon-like peptide-1 concentration

    Time frame: 2 hour

    2 hour area under the curve for plasma glucagon-like peptide-1 following breakfast consumption

Other outcomes

  1. Total fat oxidised during 60 min of exercise (g)

    Time frame: 1 hour

    Assessed by indirect calorimetry

Sponsors and collaborators

Lead sponsor

Northumbria University

Other

Registry information

Important dates

Study start
2012
Primary completion
2012
Study completion
2012
First posted
Sep 10, 2012
Registry last updated
Sep 11, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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