Skip to main content
OpenTrials
Completed

NCT Number: NCT07342894

Effect of Hemovac Drain Removal on Early Outcomes After Total Knee Arthroplasty

This study aims to evaluate whether the timing of Hemovac drain removal affects early clinical outcomes after primary total knee arthroplasty (TKA). Hemovac drains are commonly used after TKA to reduce postoperative bleeding and swelling; however, the optimal timing for drain removal remains controversial.

In this prospective observational cohort study, patients undergoing primary TKA for knee osteoarthritis will be divided into two groups according to routine clinical practice: those whose drain is removed before the first postoperative rehabilitation session and those whose drain is removed after the first rehabilitation session.

The primary outcomes include the rate of postoperative hemarthrosis, early postoperative complications, and length of hospital stay. Secondary outcomes include postoperative pain levels and functional outcomes. The results of this study may help optimize postoperative management strategies following total knee arthroplasty.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ankara Bilkent City Hospital

Ankara, Turkey (Türkiye)

About this study

Total knee arthroplasty (TKA) is a widely performed surgical procedure for the treatment of advanced knee osteoarthritis. Postoperative management often includes the use of closed suction drains, such as Hemovac systems, to reduce hematoma formation and wound complications. However, the necessity and optimal timing of drain removal remain subjects of debate.

This prospective observational cohort study is designed to compare early clinical outcomes associated with two different timings of Hemovac drain removal following primary TKA. Patients who undergo primary TKA at a single tertiary care center will be enrolled prospectively. According to routine postoperative practice, patients will be allocated into two groups: drain removal before the first postoperative rehabilitation session or drain removal after completion of the first rehabilitation session.

All patients will receive standardized surgical techniques, anesthesia protocols, postoperative care, and rehabilitation programs. Data will be collected prospectively. Primary outcomes include postoperative hemarthrosis, early postoperative complications, and length of hospital stay. Secondary outcomes include postoperative pain intensity and functional outcome measures.

This study aims to provide evidence to guide clinical decision-making regarding postoperative drain management in patients undergoing total knee arthroplasty.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18 years or older
  • Diagnosis of knee osteoarthritis
  • Undergoing primary total knee arthroplasty
  • Provided written informed consent to participate in the study

Exclusion criteria

  • Revision total knee arthroplasty
  • History of inflammatory arthritis
  • Known bleeding disorders or coagulopathy
  • Active infection or periprosthetic joint infection
  • Incomplete clinical data or loss to follow-up

Treatment and study plan

Primary outcomes

  1. Postoperative Drain Output

    Time frame: Postoperative days 0-3

    Total postoperative Hemovac drain output measured in milliliters following primary total knee arthroplasty.

Secondary outcomes

  1. Length of Hospital Stay

    Time frame: Postoperative days 0-discharge

    Duration of postoperative hospital stay measured in days.

  2. Postoperative Hemoglobin Change

    Time frame: Postoperative first 24-48 hours

    Change in hemoglobin level from preoperative baseline to postoperative measurement.

  3. Knee Society Score (KSS)

    Time frame: Postoperative 1 month

    Functional outcome assessed using the Knee Society Score.

  4. Postoperative Pain Intensity

    Time frame: Postoperative 1 month

    Pain intensity assessed using the Visual Analog Scale (VAS).

Sponsors and collaborators

Lead sponsor

Ankara City Hospital Bilkent

Other

Registry information

Official study title

Effect of Timing of Hemovac Drain Removal on Early Outcomes After Total Knee Arthroplasty

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jan 15, 2026
Registry last updated
Jan 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.