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Completed

NCT Number: NCT04830293

Effect of Head Position During Thyroidectomy on Postoperative Cognitive Functions

The aim of our study is to observe the effect of head-neck position of patients scheduled for thyroidectomy, on carotid artery blood flow, regional cerebral oxygen saturation measured using near-infrared spectroscopy technology, and postoperative cognitive dysfunction.

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Key information

Conditions

Thyroid Carotid Doppler Cerebral Perfusion Cognition Disorders Cognitive Dysfunction Endocrine System Diseases Mental Disorders Neurocognitive Disorders Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Cognitive Complications Postoperative Complications Thyroid Diseases

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Zonguldak Bülent Ecevit University Medicine Faculty

Zonguldak, Kozlu, 67600, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • undergo a total thyroidectomy operation
  • ASA I-II
  • euthyroid patients in the preoperative period

Exclusion criteria

  • Hemoglobin< 8 g / dl
  • Hypertension
  • Hyperlipidemia
  • Pregnancy
  • Patients diagnosed with diabetes mellitus
  • Cerebrovascular insufficiency
  • Known carotid artery lesion
  • Metabolic diseases
  • Any intracranial pathology present
  • Surgeries exceeding 180 minutes

Treatment and study plan

Carotis Doppler Ultrasound

Procedure

Neck was rotated about 30-45 ° to the opposite side of the image. The common carotid artery and internal jugular vein were viewed transversely on the B Mode USG image. Then, the probe was rotated approximately 90 ° and the carotid artery was visualized in the longitudinal plane. The probe and guide line were adjusted so that the Doppler angle was 60 °. The image was created with the guiding line parallel to the blood flow. After imaging of the carotid artery bifurcation, measurements were made 1 cm distal to this level.

Primary outcomes

  1. Changes in cognitive functions

    Time frame: 3 months after surgery

    determine cognitive dysfunction using mini mental state examination

Secondary outcomes

  1. Changes in Cerebral Perfusion

    Time frame: during surgery

    Changes in main carotid artery blood flow and cerebral oxygenation by using carotid doppler

Sponsors and collaborators

Lead sponsor

Zonguldak Bulent Ecevit University

Other

Registry information

Official study title

The Effect of Head Position During Thyroidectomy on Cerebral Oxygenation and Postoperative Cognitive Functions

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Apr 5, 2021
Registry last updated
Apr 5, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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