PepsiCo R&D, Gatorade Sports Science Institute
Valhalla, New York, 10595, United States
NCT Number: NCT06185595
The objective of this study is to determine the effect of consumption of drinks with varying amounts of glycerol and electrolytes on fluid balance at rest.
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Notify Me18 year–50 year
All sexes
Interventional
Not applicable
Valhalla, New York, 10595, United States
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
9.3 oz (273 ml) aliquot of one of the study beverages every 15 min for a total of 28 oz (828 ml) over a 45-min period, followed by 15 min of rest. Flavored water matched for sweetness, color. flavor, but cannot be matched for saltiness. All sodium-containing drinks will include a base blend of other electrolytes (potassium 15 mmol/L, magnesium 8 mmol/L, and calcium 5 mmol/L).
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 30, 60, 90,120 and 180 minutes
Change in body mass to the nearest 0.005 kilogram (kg) using a platform scale
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 30, 60, 90,120 and 180 minutes
As a percent (%)
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 30, 60, 90, 120 and 180 minutes
By urine mass scale in grams (g)
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 30, 60, 90,120 and 180 minutes
By USG digital pen refractometer
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 60 min, 120 min and 180 minutes
By iSTAT Blood Electrolyte and Chemistry Analyzer (CG8+ cartridge) in mmol/L
Time frame: Screening visit only
Glucometer for point of care test in mg/dL
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 60 min, 120 min and 180 minutes
By iSTAT Blood Electrolyte and Chemistry Analyzer (CG8+ cartridge) in mg/dL
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 60 min, 120 min and 180 minutes
Calculated from hematocrit and hemoglobin concentration
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 60 min, 120 min and 180 minutes
By Sigma Aldrich glycerol assay kit in mmol/L
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 30, 60, 90, 120 and 180 minutes
mmHg by automatic sphygmomanometer
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 30, 60, 90, 120 and 180 minutes
Beats per minute (bpm) by heart rate monitor
Time frame: Change from baseline (pre-beverage) to post-beverage Time 0, 30, 60, 90, 120 and 180 minutes
Visual Analog Scale (VAS) symptom rating of how you feel right now by placing a slash along a 100 millimeter (mm) vertical line anchored from 0 mm (None) to 100 mm (Severe). Fewer symptoms and lower numbers are better.
Time frame: Female participants log menstrual flow throughout study participation. The three study sessions (2-45 days apart) are scheduled to avoid menses and can be completed in the same menstrual cycle, or in 3 different cycles (3 different months) if needed.
Date of last menstrual period by self-report of female participant
PepsiCo Global R&D
Industry
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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