Federal University of Para
Belém, Pará, 66075-110, Brazil
NCT Number: NCT04207450
This randomized, placebo-controlled, triple-blind trial aims to evaluate the effect of glutaraldehyde associated or not with 37% phosphoric acid conditioning on dentin hypersensitivity reduction after non-surgical periodontal treatment, and its durability after 15 and 30 days. desensitizing treatment. Additionally, investigate the impact of these treatments on health-related quality of life. The investigators selected patients who, after scraping and planing procedures, presented at least 2 teeth meeting the following inclusion criteria: presence of gingival recession without or with a periodontal pocket up to 5mm probing depth, which presented painful sensitivity response to tactile stimulus. and evaporative. Subjects were randomized into 3 groups: Placebo Group (GP) - Placebo Gel application followed by Placebo solution (distilled water); GPG- Placebo Gel application followed by application 5% aqueous glutaraldehyde solution; GSG - Application of 37% phosphoric acid followed by 5% aqueous glutaraldehyde solution. The sensitivity of the dental elements was evaluated by pain stimuli (tactile and evaporative) with the aid of a Visual Analog Scale (VAS). A questionnaire was applied to patients with the objective of capturing psychosocial experiences, prior to treatment and one month after its completion, to assess the impact of desensitizing treatment on health-related quality of life. Data will be collected and appropriate statistical tests will be applied.
Looking for future studies?
Notify Me18 year–50 year
All sexes
Interventional
Not applicable
Belém, Pará, 66075-110, Brazil
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Placebo gel application followed by placebo solution application (distilled water)
Placebo gel followed by 5% aqueous glutaraldehyde solution
37% phosphoric acid application followed by 5% aqueous glutaraldehyde solution
Time frame: Immediately after the intervention
Evaluation of pain (dentin sensitivity) by applying tactile (exploratory probe pressure) and evaporative (air blast) stimuli on exposed dentin. Sensitivity will be measured using the Thomas Schiff scale from 0 to 3. Zero means absent dentin sensitivity and three means severe dentin sensitivity.
Time frame: Immediately after the intervention
A self-reported questionnaire was applied by the patients with the objective of capturing psychosocial experiences, previous treatment and one month after its completion, aiming to evaluate the impact of desensitizing treatment on health-related quality of life.
Universidade Federal do Para
Other
Effect of Glutaraldehyde on Dentin Hypersensitivity After Non-surgical Periodontal Treatment: a Triple-blind Randomized Clinical Trial.
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07317128
Dentin Sensitivity, Stomatognathic Diseases
Wuhan, Hubei, China
View Trial DetailsNCT07352956
Dentin Sensitivity, Stomatognathic Diseases
Chengdu, Sichuan, China
View Trial DetailsNCT06378255
Dentin Sensitivity, Stomatognathic Diseases
Beijing, Beijing Municipality, China
View Trial DetailsNCT06608368
Dentin Sensitivity, Stomatognathic Diseases
Mississauga, Ontario, Canada
View Trial Details