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OpenTrials
Completed

NCT Number: NCT01948453

Effect of Garlic Tablet Some Indicators Related to Atherosclerosis

The purpose of this study is to determine whether garlic in adjunct to conventional medical treatment is effective in improving carotid intima media thickness (CIMT), Flow mediated dilation (FMD) and plasma lipid profile or c-reactive protein of coronary artery disease (CAD) patients.

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Key information

Conditions

Coronary Artery Disease Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Coronary Disease Heart Diseases Myocardial Ischemia Vascular Diseases

Age range

25 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Rajaei Cardiovascular, Medical & Research Center

Tehran, Iran

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • angiography confirmed coronary artery disease
  • lack of consistent use of the garlic in the last month

Exclusion criteria

Change in type of medication during study

Treatment and study plan

Garlic

Dietary Supplement

Garlic tablet in adjunct to medical treatment

Primary outcomes

  1. Carotid Intima Media Thickness

    Time frame: 12 weeks

    Change from baseline and compared to placebo group in Carotid Intima Media Thickness at 12 weeks

Secondary outcomes

  1. Flow-mediated dilatation

    Time frame: 12 weeks

    Change from baseline and compared to placebo group in Flow-mediated dilatation at 12 weeks

Other outcomes

  1. plasma levels of Alanine Aminotransferase, Aspartate Aminotransferase, creatinine, lipid profile, C-Reactive Protein

    Time frame: 12 weeks

    Change from baseline in plasma levels at 12 weeks

Sponsors and collaborators

Lead sponsor

Shahid Beheshti University

Other

Registry information

Official study title

Effect of Garlic Tablet on Carotid Intima Media Thickness and Flow-mediated Dilation in Patients Undergoing Angioplasty

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Sep 23, 2013
Registry last updated
May 28, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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