Effect of Extracorporeal Shockwave Ther… | Clinical Trial

Key information

Conditions

Neurodermatitis Dermatitis Skin Diseases Skin Diseases, Eczematous Skin and Connective Tissue Diseases

Age range

55 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Suez Canal University Hospital

Ismailia, Egypt

About this study

Based on the occurrence of side effects caused by conventional medication for prolonged employment, dermatologists and patients show solicitude for multifaceted effective methods to control the chronic and relapsing nature of neurodermatitis.

Although new modalities are continuously coming up for pruritus, there remains a great gap for providing symptom relief.

Furthermore, there is a lack in the quantitative knowledge and information in the published studies about benefits of shockwave therapy on the treatment of pruritus in neurodermatitis patients. So, this study is designed to outline the therapeutic efficacy of shockwave therapy on the treatment of pruritus in neurodermatitis patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age range between 55:75 years.
Male and female patients will participate in the study.
All patients have neurodermatitis.
All patients will be received the same approach of medication and nursing care.
All patients enrolled in the study will have their informed consent.

Exclusion criteria

Patients diagnosed with cancer.
Pregnant woman.
active infection.
Patients with any systemic diseases that may interfere with the objectives of the study.
Cardiac pacemakers or other implantable devices.
Current anticoagulation use.
Any other cause of itching

Treatment and study plan

Shockwave therapy

Device

The procedures for Extracorporeal Shockwave Therapy (ESWT) involve several steps. First, the patient is positioned comfortably, and the physiotherapist explains the treatment procedure. Before the session begins, the device cables are checked for proper functioning. The shockwave type used is Non-Focused/Radial, with a treatment duration not exceeding 10 minutes. The frequency is set at 4 Hz, and the intensity ranges from 0.05 to 0.20 mJ/mm². Each session involves a total of 1000 to 2000 shocks. The treatment consists of four sessions, each held once a week.

Emollients & corticosteroids

Drug

Patients in both groups will receive emollients & corticosteroids for one month.

Primary outcomes

5-D Itching Scale

Time frame: one month

The 5-D Itching Scale will be used to assess the improvement of cases by evaluating pruritus severity. Patients will complete the scale both before starting the treatment and at four sessions following the treatment. The following steps will be followed during the assessment: the patient will be positioned comfortably (sitting position), the physiotherapist will explain the pruritus symptoms score to the patient, and the patient will determine their points on the 5-D itch scale.

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Oct 3, 2025
Registry last updated: Mar 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed