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NCT Number: NCT02348229

Effect of Enhanced Recovery After Surgery (ERAS) on C-reactive and Visceral Proteins

The investigators designed a prospective randomized, controlled clinical trial then recruited 149 consecutive advanced gastric cancer patients. Further divided into a ERAS group (n=73) and a conventional pathway group (n=76). Surgical technique in both groups was same laparoscopic-assisted gastrectomy with D2 lymphadenectomy. Compared outcomes included clinical parameters and serum indicators.

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Key information

Conditions

Gastric Cancer Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Neoplasms Neoplasms by Site Stomach Diseases Stomach Neoplasms

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Enhanced recovery after surgery combined with laparoscopic-assisted gastrectomy was successfully carried out in this study. Recovery parameters such as the length of time to return to normal diet,mean hospital stay (d) were recorded.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18-75 years old
  • Diagnosis confirmed by the endoscopic biopsy and total-body CT scan
  • No history of the chronic renal disease ,chronic liver disease, cardiopulmonary dysfunction, ASA score≦3
  • No neoadjuvant chemotherapy and radiotherapy
  • No digestive obstruction and distant metastasis

Exclusion criteria

  • Conversion to open gastrectomy
  • A large amount of bleeding leading(>500ml)
  • Patients withdrew their consent

Treatment and study plan

ERAS protocols

Procedure

Normal meal allowed until 6 h before surgery and Carbohydrate drink until 2 h before surgery

conventional pathway group

Procedure

No solid foods at dinner before surgery and no liquids 12 h before surgery. Routine bowel preparation Nasogastric placement on the morning of surgery

Primary outcomes

  1. Compartition of postoperative hospital stay

    Time frame: up to 30 days after the operation

Secondary outcomes

  1. Change from baseline in C-Reactive Protein( CRP) and visceral proteins level

    Time frame: baseline and 5 days

    1day before and 1-5days after operation

Sponsors and collaborators

Lead sponsor

The First Hospital of Jilin University

Other

Registry information

Official study title

Effect of Enhanced Recovery After Surgery (ERAS) on C-reactive and Visceral Proteins in Patients With Advanced Gastric Cancer

Acronym: ERASAG

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Jan 28, 2015
Registry last updated
Jan 28, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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