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NCT Number: NCT07622654

Effect of Emotion-Focused Acceptance and Commitment Therapy on Obsessive-Compulsive Disorder Symptom Severity

This study aims to investigate the effect of Emotion-Focused Acceptance and Commitment Therapy (ACT) group psychotherapy on obsessive-compulsive disorder (OCD) symptom severity. Participants with OCD will be randomly assigned to either an ACT-based group psychotherapy arm or a supportive group psychotherapy arm. Each arm consists of 10 to 12 weekly sessions of 2 hours. Symptom severity, psychological flexibility, emotional awareness, functioning and quality of life will be assessed before and after the intervention.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Goztepe Prof. Dr. Suleyman Yalcin City Hospital

Istanbul, 34722, Turkey (Türkiye)

Location status: Recruiting

Location contact

Beyza Baran Boz

SUB_INVESTIGATOR

Kaasım Fatih Yavuz

SUB_INVESTIGATOR

Mehmet Emrah Karadere

CONTACT

[email protected]

905332651664

Mehmet Emrah Karadere

PRINCIPAL_INVESTIGATOR

About this study

This randomized controlled trial investigates the efficacy of an Emotion-Focused Acceptance and Commitment Therapy (ACT) protocol in adults diagnosed with Obsessive-Compulsive Disorder (OCD). Participants will be recruited from the psychiatry outpatient clinic of Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi.

Eligible participants will be randomly assigned to one of two arms:

ACT-based group psychotherapy: Structured group therapy targeting emotional awareness, acceptance of emotional experiences, cognitive defusion, present-moment focus, values clarification, and committed action. Groups will consist of 8-10 participants, meeting once weekly for 10-12 sessions of 2 hours each.

Supportive group psychotherapy (active control): Unstructured supportive group therapy aimed at providing emotional support, enhancing coping with stress, and maintaining current functioning. Groups will consist of 8-10 participants, meeting once weekly for 10-12 sessions of 2 hours each.

Assessments will be conducted at baseline and post-treatment using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Dimensional Obsessive-Compulsive Scale (DOCS), Vancouver Obsessional Compulsive Inventory (VOCI), SF-36 Quality of Life Scale, Acceptance and Action Questionnaire-II (AAQ-II), Hospital Anxiety and Depression Scale (HADS), and Toronto Alexithymia Scale (TAS-20).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of Obsessive-Compulsive Disorder according to DSM-5 criteria
  • Age between 18-65 years
  • Minimum literacy level
  • Willingness to participate and providing informed consent

Exclusion criteria

  • Age over 65 years
  • Diagnosis of alcohol or substance use disorder
  • Comorbid psychotic disorder or intellectual disability
  • Any change in psychiatric treatment (medication or psychotherapy) in the last 3 months
  • Comorbid psychiatric disorder that would impair group therapy compliance
  • History of cognitive impairment due to dementia, organic brain syndrome or other neurological/organic pathology

Treatment and study plan

Emotion-Focused Acceptance and Commitment Therapy (ACT) Group Psychotherapy

Behavioral

Structured group psychotherapy based on ACT principles targeting emotional awareness, acceptance of emotional experiences, cognitive defusion, present-moment focus, values clarification and committed action. Sessions are conducted face-to-face, once weekly, 2 hours per session, for 10-12 weeks.

Primary outcomes

  1. Obsessive-Compulsive Symptom Severity

    Time frame: Baseline and 10-12 weeks (post-treatment)

    Change in OCD symptom severity measured by Yale-Brown Obsessive Compulsive Scale (Y-BOCS) from baseline to post-treatment.

  2. OCD Symtom Severity- DOCS

    Time frame: Baseline and 10-12 weeks

    Change in OCD symptom severity measured by Dimensional Obsessive-Compulsive Scale (DOCS) from baseline to post treatment.

Study contacts

Contact information is provided by the study sponsor or research team.

Mehmet Emrah Karadere

CONTACT

[email protected]

05332651664

Sponsors and collaborators

Lead sponsor

Mehmet Emrah Karadere

Other

Collaborators

  • Goztepe Prof Dr Suleyman Yalcın City Hospital

Registry information

Official study title

The Effect of Emotion-Focused Acceptance and Commitment Therapy on Obsessive-Compulsive Disorder Symptom Severity: A Randomized Controlled Trial

Acronym: ACT-OCD

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jun 3, 2026
Registry last updated
Jun 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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