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Completed

NCT Number: NCT07365878

Effect of Dry Needling on Insulin Resistance in Obese Post Menopausal Women

The aim of the study is to determine the effect Dry Needling of on insulin resistance in obese postmenopausal women.

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Key information

Age range

48 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Shymaa Mohammed

Cairo, Egypt

About this study

Insulin resistance and abdominal obesity have a negative impact on quality of life of postmenopausal women. Obesity and, more specifically, the level of intra-abdominal fat, are positively associated with cardiovascular disease and cardiovascular disease risk factors such as increased plasma lipids and lipoproteins, hyperinsulinemia, and insulin resistance. This study has shown associations among menopause, body fat, and body fat distribution, suggesting that increased abdominal fat distribution could partially mediate the increased cardiovascular disease risk of postmenopausal women .

Abdominal obesity can reflect excess of visceral fat tissue or subcutaneous or both. Visceral fat contributes to the pathogenesis of glucose intolerance and insulin resistance. Insulin resistance is an impaired condition of glucose absorption that induced by insulin .It represents a significant medical and socioeconomic issue impacting women's health and quality of life. So there is clinical experience and documentation for the effectiveness of Dry Needling in the treatment of insulin resistance in obese post-menopausal women.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • • All participants post-menopausal from at least 3 years.
  • All participants' ages will be ranged from 48-60 years old.
  • All participants BMI will exceed 25-30 kg/m2.
  • All participants waist hip ratio will be equal or more than 0, 90.

Exclusion criteria

  • • Surgical liposuction within the last 12 months.
  • Untreated hypo- or hyperthyroidism.
  • Uncontrolled liver, kidney or cardiovascular disease or diabetes.
  • Implanted pacemaker or metal implant.
  • History of thrombophlebitis, any hematological disease.
  • No past or present neurological and musculoskeletal disorders that will have affected health condition.
  • No smoking and drinking habits.
  • No psychological problems.

Treatment and study plan

Dry needle

Other

Dry Needle has been used to treat obesity. Clinical research has found that it is particularly effective for abdominal fat loss.Dry needling in the abdominal region requires an in-depth understanding of the underlying anatomy due to significant safety risks.

abdominal exercises, and medical standard care for insulin resistance

Other

To reduce belly fat, combine core-strengthening exercises like planks, bicycle crunches, and leg raises with overall fat-burning cardio (walking, running) and a healthy diet

Primary outcomes

  1. HOMA-IR

    Time frame: 4 months

    Outcome measures, HOMA-IR (Homeostasis Model Assessment) will be used to assess insulin resistance. HOMA-IR is a model of interactions between glucose and insulin dynamics that is then used to predict fasting steady-state glucose and insulin concentrations for a wide range of possible combinations of insulin resistance and β-cell function.

Secondary outcomes

  1. ultrasound

    Time frame: 4 months

    Abdominal fat thickness will be assessed by ultrasound (Aplio 500-model TUS-A500, fundamentals (2B77-004EN*M)

  2. BMI by kg/m2

    Time frame: 4 months

    weight and height will be combined to report BMI in kg/m^2

  3. waist circumferences by tape

    Time frame: 4 months

  4. The surface under the cumulative ranking curve (SUCRA)

    Time frame: 4 months

    The surface under the cumulative ranking curve (SUCRA) was used to rank and compare the effects of different types of exercise. SUCRA values range from 0 to 100, where 100 indicates the best treatment with no uncertainty and 0 indicates the worst treatment with no uncertainty. Thus, higher SUCRA values indicated the better effects of an exercise intervention prior to and after four-month treatment duration for both groups.

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Effect of Dry Needling on Insulin Resistance in Obese Post- Menopausal Women

Acronym: Dry needle

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jan 26, 2026
Registry last updated
Jan 26, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.