Skip to main content
OpenTrials
Completed

NCT Number: NCT03662113

Effect of Domperidone on Completion Rate of Vedio Capsule Endoscopy

Video capsule endoscopy (VCE) has become an established technique to investigate the presence of small bowel pathology. But the limited battery life of capsules can lead to incomplete small bowel visualization. There is a rationale to use prokinetic agents prior to VCE reduce the chances of an incomplete small bowel examination via decrease gastric transit time (GTT). Investigators are aimed to prospectively compare the completion rate of VCE in pediatric patients receiving prokinetic with those receiving no prokinetic.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Capsule Endoscopy Pediatric Disorder

Age range

3 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Children's hospital of Fudan university

Shanghai, Shanghai Municipality, 201102, China

About this study

Eligible children were randomly divided into two groups: domperidone prior to VCE and water prior to VCE. The primary outcome measure was the completion rate. Secondary outcome measures included the GTT and SBTT.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Indications of capsule endoscopy;
  • Informed consent form obtained.

Exclusion criteria

  • Contraindication of capsule endoscopy;
  • Domperidone allergy;
  • Unwilling to participate.

Treatment and study plan

Domperidone

Drug

5ml Domperidone prior to VCE

Other names: simethicone

Water

Dietary Supplement

5ml water prior to VCE

Other names: simethicone

Primary outcomes

  1. Completion rate of capsule endoscopy

    Time frame: assessed through study completion, an average of 1 year

    CE was considered complete when the cecum was reached within recording time.

Secondary outcomes

  1. Gastric transit time (GTT)

    Time frame: assessed through study completion, an average of 1 year

    The GTT was defined as the time, in minutes, from the first image of the stomach until the first image of the duodenum.

  2. small bowel transit time (SBTT)

    Time frame: assessed through study completion, an average of 1 year

    The SBTT was defined as the passage time, in minutes, from the first image of the duodenum until the first image of the cecum.

Sponsors and collaborators

Lead sponsor

Children's Hospital of Fudan University

Other

Registry information

Official study title

Effect of Domperidone on Completion Rate of Vedio Capsule Endoscopy: a Prospective Randomized Controlled Study

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Sep 7, 2018
Registry last updated
Dec 17, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.