Skip to main content
OpenTrials
Completed

NCT Number: NCT07533760

Effect of Different Volumes of Erector Spinae Plane Block on Postoperative Opioid Consumption After Total Abdominal Hysterectomy

his study aims to investigate the effects of different volumes of ultrasound-guided erector spinae plane block (ESPB) on postoperative pain and opioid consumption in patients undergoing total abdominal hysterectomy. The researchers aim to determine whether varying the volume of local anesthetic in the ESPB can reduce the amount of morphine required by patients and improve pain scores during the first 24 hours after surgery.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Postoperative Pain Abdominal Hysterectomy Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Necmettin Erbakan University Faculty of Medicine

Konya, 42040, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged between 18 and 65 years.
  • Patients with American Society of Anesthesiologists (ASA) physical status I-III.
  • Patients scheduled to undergo elective total abdominal hysterectomy surgery.

Exclusion criteria

  • Obese patients (Body Mass Index > 30 kg/m²).
  • Patients with local skin infection at the site of needle insertion.
  • Patients with a known allergy to any of the medications used in the study.
  • Patients with coagulopathy.
  • Patients with chronic opioid consumption.
  • Patients with an inability to use the Patient-Controlled Analgesia (PCA) device.
  • Patients with advanced hepatic or renal failure.
  • Patients who refuse to participate in the study.

Treatment and study plan

Erector Spinae Plane Block

Procedure

The ESPB will be performed at the T8-T9 vertebral levels. Patients will be placed in the prone position, and skin preparation will be performed with 10% povidone-iodine. Local anesthesia of the skin and subcutaneous tissue will be provided with 3 ml of 2% lidocaine at the target injection site.

Under ultrasound guidance, a sterile-covered linear probe (8 MHz) will be used to visualize the T8 spinous process in the horizontal plane at the midline. The probe will then be rotated to the longitudinal plane, approximately 3 cm lateral to the midline, to visualize the transverse process and the overlying erector spinae muscle. A 22-gauge, 80-mm block needle will be advanced in-plane in a cranio-caudal direction until it contacts the transverse process. The needle was then withdrawn slightly, and its placement between the erector spinae muscle and the transverse process was confirmed through hydrodissection. The patients in Group I received 20 ml of 0.25% (2.5 mg/ml) bupivacaine hydrochloride

Primary outcomes

  1. Total Morphine Consumption

    Time frame: First 24 hours postoperatively

    The total amount of morphine (in milligrams) consumed by the patient via the Patient-Controlled Analgesia (PCA) device.

Secondary outcomes

  1. Numerical Rating Scale (NRS) Scores for Pain

    Time frame: At postoperative 30 minutes, 2nd, 6th, 12th, and 24th hours

    Pain intensity measured at rest and during movement (dynamic) using a scale from 0 (no pain) to 10 (worst possible pain).

  2. Number of Blocked Dermatomes

    Time frame: 20 minutes after the block procedure

    The number of dermatomes with loss of hot-cold sensation above and below the surgical incision.

Sponsors and collaborators

Lead sponsor

Şule Arıcan

Other

Registry information

Official study title

Comparison of the Effectiveness of Erector Spinae Plane Block Administered at Different Volumes on Postoperative Opioid Consumption and Analgesia in Patients Undergoing Total Abdominal Hysterectomy: A Randomized, Prospective, Double-Blind Study

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Apr 16, 2026
Registry last updated
Apr 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.