Effect of Different Root Canal Sealers on Oxidative Stress Markers

Inclusion criteria

• Systemically healthy, ASA1 patients,
• Phase 1 periodontal treatment was performed,
• Diagnosed with chronic apical periodontitis in a single tooth with 2 or more roots in the mouth,
• The lesion measured <2 cm on radiographic evaluation,
• The vitality of the tooth was checked by EPT (Ai-Pex, Woodpecker, China) and Cold test (Cerkamed, Poland) and confirmed to be devitalised,
• Socioculturally able to participate in the treatment,
• Individuals who did not smoke or drink alcohol

Exclusion criteria

• Patients who have used antibiotics in the last three months and analgesics in the last two weeks
• Patients who smoke and/or abuse alcohol
• Patients younger than 18 years or older than 45 years,
• Patients with controlled or uncontrolled systemic disease and life-threatening conditions (ASA 2,3,4,5,6)
• Pregnant or lactating women,
• Patients with poor oral hygiene,
• Patients who had head and neck radiotherapy,
• With obesity,
• Active periodontal disease,
• Periodontal pocket depth over 3mm,
• There is enough loss of material in the relevant tooth to prevent adequate isolation or to require post placement,
• Clinical examination of the relevant tooth showing symptoms in percussion-palpation,
• Radiographically, the lesion is seen in relation to anatomical formations such as the mandibular canal and maxillary sinus,
• Patients who required prophylactic antibiotic use before invasive dental procedures were excluded from the study.
• Patients who did not attend the follow-up appointment and patients who experienced complications during expansion (instrument seperation, perforation, etc.) were excluded from the study.