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OpenTrials
Completed

NCT Number: NCT01802541

Effect of Diacylglycerol Oil on Risk Factors of Type 2 Diabetes and Complicating Disease, and Mechanism

Diacylglycerol oil has been shown to lower postprandial and fasting serum triacylglycerol levels and reduce body fat. The investigators hypothesize that replacing dietary fat with diacylglycerol oil reduces excess body fat in type 2 diabetic patients and that diacylglycerol oil has a beneficial effect on cardiovascular risk factors in Chinese type 2 diabetic patients.

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Key information

Conditions

Insulin Sensitivity Cardiovascular Disease Cardiovascular Diseases Diabetes Mellitus Diabetes Mellitus, Type 2 Endocrine System Diseases Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Metabolic Diseases Nutritional and Metabolic Diseases Type 2 Diabetes

Age range

40 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Type 2 diabetic patients, blood sugar levels were stabilized between 7.0-10.0 mmol/L
  • Male, aged 40 - 70 years old, Female, aged post-menopausal - 70 years old.
  • Overweight/obese patients (BMI 25 - 40 kg/m2)
  • Currently under diet therapy for diabetes mellitus
  • Understands the procedures and willing to participate in the study

Exclusion criteria

  • Patients who unwilling to give informed consent
  • Type 1 diabetic patients
  • Familial hyperlipemia patients or blood triacylglycerol concentration > 400 mg/dl
  • Patients with a history of cardiovascular disease and/or arteriosclerotic disease
  • Patients with a history of cerebrovascular disease
  • Patients with serious hepatic disease and/or renal disease
  • Patients with malignancy
  • Participation in another clinical study within 30 days prior to screening period.
  • Has a condition the doctor in charge believes would interfere with evaluation of the subject, or may put subject at undue risk

Treatment and study plan

diacylglycerol oil

Dietary Supplement

triacylglycerol oil

Dietary Supplement

Primary outcomes

  1. insulin resistance

    Time frame: 120 days

Sponsors and collaborators

Lead sponsor

Zhejiang University

Other

Registry information

Important dates

Primary completion
2006
First posted
Mar 1, 2013
Registry last updated
Mar 1, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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