Shaukat Khanum Memorial Cancer Hospital and Research Centre
Lahore, Pubjab, 54782, Pakistan
Completed
NCT Number: NCT07180810
Effect of Dexmedetomidine Infusion on Post Anesthesia Discharge Time
A randomised control trial evaluating the effect of low dose dexmedetomidine infusion on post anesthesia discharge time in patients of day case breast cancer surgery compared with placebo infusion. The primary outcome was to compare the frequency of early discharge in each group.
Completed
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Notify MeKey information
Age range
18 year–60 year
Sex eligibility
Female
Study type
Interventional
Phase
Not applicable
Primary location
About this study
A prospective Randomised control trial evaluating the effect of low dose dexmedetomidine infusion on post anesthesia discharge time in patients of day case breast cancer surgery compared with placebo infusion. The primary outcome was to compare the frequency of early discharge in each group. Early discharge was defined as within two hours. The sample size was of 82 female patients with a specific inclusion and exclusion criteria. Randomisation was done through computer software and the trial was double blinded. SPSS version 22 will be used for data analysis.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Age 18-60 yrs, ASA 1 and 2, elective breast cancer surgery
Exclusion criteria
- BMI greater than 35, CKD stage 3 or greater, known drug allergy to study drug, bradycardia, history of PONV, patients on antiepileptics
Treatment and study plan
Dexmedetomidine infusion low dose
Druglow dose dexmedetomidine infusion at rate 0.6mcg/kg/hour rate .
Group B receiving normal saline
DrugNormal saline infusion at rate 0.6mcg/kr/hour rate
Primary outcomes
-
Frequency of early discharge
Time frame: 120 minutes
post anesthesia discharge time within 2 hours
Sponsors and collaborators
Lead sponsor
Shaukat Khanum Memorial Cancer Hospital & Research Centre
Other
Registry information
Official study title
Effect of Low Dose Intravenous Dexmedetomidine on Post Anesthesia Discharge After Day Case Breast Cancer Surgery
Important dates
- Study start
- 2023
- Primary completion
- 2025
- Study completion
- 2025
- First posted
- Sep 18, 2025
- Registry last updated
- Sep 23, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.