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NCT Number: NCT07740876

Effect of Dental Education Duration on Halitosis and Associated Factors

The study population will consist of undergraduate dental students enrolled at Recep Tayyip Erdoğan University Faculty of Dentistry. A total of 100 students, including 50 first-year and 50 fifth-year dental students, will be included. Eligible participants will be healthy students who meet the study criteria and provide written informed consent. Participants will undergo subjective and objective halitosis assessments, including questionnaires, organoleptic evaluation, volatile sulfur compound measurements, tongue coating assessment, and DMFT index recording.

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Key information

Age range

18 year–25 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Recep Tayyip Erdoğan University

Rize, Turkey (Türkiye)

About this study

Halitosis, also known as oral malodor, is a multifactorial condition primarily associated with volatile sulfur compounds produced by bacterial metabolism in the oral cavity. Although previous studies have investigated factors related to halitosis, limited information is available regarding the influence of dental education duration on objective halitosis measurements and associated behavioral and psychological factors.

This study will compare first-year and fifth-year dental students to evaluate whether the duration of dental education is associated with differences in halitosis levels. Objective measurements, including organoleptic assessment and portable digital halitometer measurements of volatile sulfur compounds, will be combined with subjective assessments of halitosis perception, oral hygiene habits, perceived stress levels, tongue coating index, and DMFT index.

The findings of this study may contribute to understanding the relationship between dental education, oral health awareness, lifestyle behaviors, psychological factors, and halitosis among future dental professionals.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Undergraduate students enrolled in the Faculty of Dentistry at Recep Tayyip Erdoğan University.
  • First-year and fifth-year dental students who agree to participate in the study and provide written informed consent.
  • Healthy students with no systemic diseases affecting oral health or halitosis assessment.
  • Students with normal nasal breathing ability.
  • Participants who comply with the pre-assessment instructions required for accurate halitosis measurements.
  • Participants who are able to complete the questionnaires and clinical evaluation procedures.

Exclusion criteria

  • Students with systemic diseases that may affect halitosis, including diabetes mellitus, respiratory disorders, liver cirrhosis, chronic renal failure, or gastrointestinal disorders.
  • Participants with active upper respiratory tract infection, sinusitis, tonsilloliths, or other conditions affecting oral odor.
  • Participants with a history of antibiotic use within the previous 3 weeks.
  • Pregnant or breastfeeding students.
  • Students unwilling to provide written informed consent.
  • Students receiving active orthodontic treatment or requiring orthognathic treatment.
  • Participants unable to comply with the pre-assessment restrictions (dietary restrictions, oral hygiene restrictions, smoking and product-use restrictions) before halitosis evaluation.

Treatment and study plan

Primary outcomes

  1. Halitosis Level Assessed by Organoleptic Evaluation

    Time frame: Baseline

    Halitosis level will be assessed using the organoleptic evaluation method performed by two trained evaluators. The perceived odor intensity will be scored according to a standardized 0-5 scale: 0 = no odor, 1 = barely noticeable odor, 2 = slight but noticeable odor, 3 = moderate odor, 4 = strong odor, and 5 = extremely strong odor. The mean score of the two evaluators will be recorded as the organoleptic halitosis score. A score of ≥2 will be considered indicative of halitosis.

  2. Volatile Sulfur Compound (VSC) Levels Measured by Portable Digital Halitometer

    Time frame: Baseline

    Exhaled breath volatile sulfur compound (VSC) levels will be measured using a portable digital halitometer. Three measurements will be obtained from each participant, and the mean value will be recorded in parts per billion (ppb). Values ≥125 ppb will be considered indicative of halitosis.

  3. Self-Perceived Halitosis Level Assessed by Visual Analog Scale (VAS)

    Time frame: Baseline

    Participants' self-perception of oral malodor will be evaluated using a Visual Analog Scale (VAS) ranging from 0 to 10, where 0 indicates no perceived halitosis and 10 indicates severe perceived halitosis.

Secondary outcomes

  1. Perceived Stress Level Assessed by the Perceived Stress Scale (PSS)

    Time frame: Baseline

    Participants' perceived stress levels will be evaluated using the Turkish validated version of the Perceived Stress Scale. The scale consists of 8 items scored on a 5-point Likert scale, with total scores ranging from 0 to 32. Higher scores indicate higher perceived stress levels.

  2. Tongue Coating Index (TCI)

    Time frame: Baseline

    Tongue coating will be evaluated visually on the dorsal surface of the tongue using the Tongue Coating Index. Scores range from 0 to 3: 0 = no coating, 1 = coating covering less than one-third of the tongue surface, 2 = coating covering less than two-thirds, and 3 = coating covering more than two-thirds of the tongue surface.

  3. Dental Caries Experience Assessed by DMFT Index

    Time frame: Baseline

    Dental caries experience will be assessed using the DMFT index, which records the number of decayed (D), missing due to caries (M), and filled (F) teeth. The total DMFT score will be calculated as D + M + F.

Study contacts

Contact information is provided by the study sponsor or research team.

Dilara Nil GÜNAÇAR

CONTACT

[email protected]

+905412940104

Sponsors and collaborators

Lead sponsor

Recep Tayyip Erdogan University Training and Research Hospital

Other

Registry information

Official study title

Assessment of the Relationship Between Duration of Dental Education and Halitosis, Oral Hygiene Behaviors, and Associated Factors Among Dental Students

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Aug 3, 2026
Registry last updated
Aug 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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