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Completed

NCT Number: NCT04112004

Effect Of Delta Sodium on the Postoperative Outcomes in Liver Transplant Recipients

We analyzed the association of delta sodium levels with their effect on post liver transplant outcomes in consecutive patients undergoing liver transplantation. Records were analyzed for electrolytes and outcome measures, and data was analyzed.

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Key information

Conditions

Liver Transplant; Complications Electrolyte Disturbance Pathologic Processes Pathological Conditions, Signs and Symptoms Perioperative/Postoperative Complications Postoperative Complications

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Institute of Liver and Biliary Sciences

New Delhi, National Capital Territory of Delhi, 110070, India

About this study

Preoperative hyponatremia was identified in patients. The mean change in sodium in hyponatremic patients was compared with inpatients with normal sodium levels. The impact of the delta sodium levels with short-term outcomes, such as duration of intubation, intensive care unit length of stay were analyzed with univariate and multivariate logistic regression analyses.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All liver transplant recipients between Jan 2011 to Jan 2017
  • Records available

Exclusion criteria

  • Acute fulminant liver failure
  • All patients less than 18 years
  • Re operated cases
  • Pregnant patients

Treatment and study plan

Collecting sodium reports and outcome measures

Other

Primary outcomes

  1. change in serum sodium in liver transplant recipients

    Time frame: 1 day

    difference between baseline and postoperative sodium in liver transplant recipients

  2. post transplant mortality

    Time frame: 1 month

    post transplant mortality after liver transplantation

Secondary outcomes

  1. post operative neurological complications

    Time frame: 1 month

    Post operative neurological complications after liver transplantation

  2. duration of mechanical ventilation

    Time frame: 1 month

    duration of mechanical ventilation after liver transplantation

  3. Duration of hospital stay

    Time frame: 1 month

    Hospital stay after liver transplantation

  4. Duration of ICU stay

    Time frame: 1 month

    Duration of ICU stay after liver transplantation

Sponsors and collaborators

Lead sponsor

Institute of Liver and Biliary Sciences, India

Other

Registry information

Official study title

Effect of Perioperative Delta Sodium on Outcomes in Liver Transplant Recipients

Acronym: SOLT

Important dates

Study start
2011
Primary completion
2017
Study completion
2017
First posted
Oct 2, 2019
Registry last updated
Oct 2, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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