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Completed

NCT Number: NCT07676838

Effect of Curd Cheese on Metabolic Health in Adults

This randomized controlled trial aims to evaluate the effects of a diet supplemented with curd cheese on anthropometric measurements, glycemia, and lipid profile in overweight adults. Participants aged 40-64 years with a BMI above 25 will be randomly assigned to an intervention group receiving 100 g of curd cheese at breakfast for 8 weeks or to a control group receiving a standard healthy diet without curd cheese. Primary outcomes include changes in fasting blood glucose and HbA1c, while secondary outcomes are changes in body composition, waist circumference, and lipid profile (HDL, LDL, triglycerides, total cholesterol).

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Key information

Age range

40 year–64 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Darıca Healthy Life Center

Kocaeli, DARICA, 41700, Turkey (Türkiye)

About this study

Metabolic disorders, including obesity, dyslipidemia, and type 2 diabetes mellitus, are major public health concerns worldwide. Dietary protein quality and source have been shown to play important roles in regulating glucose and lipid metabolism. Whey-derived proteins are rich in branched-chain amino acids and bioactive peptides that may enhance insulin sensitivity, promote satiety, and improve lipid profiles.

Curd cheese (lor cheese) is a traditional dairy product obtained during whey processing, characterized by its high-quality protein, low fat content, and rich calcium composition. It represents an affordable and accessible food that could be incorporated into dietary interventions targeting metabolic health improvement.

This study aims to investigate the effects of a curd cheese-supplemented diet on anthropometric parameters, glycemic control (including fasting glucose and HbA1c), and lipid profile (total cholesterol, HDL, LDL, and triglycerides) in adults attending the Darıca Healthy Life Center. Participants will follow a controlled dietary intervention with or without curd cheese for eight weeks.

The hypothesis of this study is that regular consumption of curd cheese as part of a balanced diet may improve metabolic parameters through increased protein intake, better glycemic regulation, and enhanced lipid metabolism.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Individuals aged 40-64 years.
  • Body Mass Index (BMI) greater than 25 kg/m².
  • Individuals who voluntarily applied to the Darıca Healthy Life Center and agreed to participate in the study.
  • Individuals who have had HbA1c, glucose, and lipid profile measurements within the past month, or will have these measurements taken as part of this study.
  • Individuals who are able to comply with the curd cheese-supplemented dietary intervention for at least 8 weeks.
  • Individuals who have signed the written informed consent form.

Exclusion criteria

  • Individuals diagnosed with diabetes mellitus.
  • Individuals with chronic diseases such as renal, hepatic, or cardiac failure.
  • Individuals with lactose intolerance or allergy to milk and dairy products.
  • Pregnant or lactating women.
  • Individuals with restricted protein intake for any medical reason.
  • Individuals who have participated in another dietary intervention program within the last 3 months.
  • Individuals diagnosed with psychiatric disorders requiring regular treatment.
  • Individuals with irregular lifestyles or communication difficulties that may prevent adherence to the dietary intervention.

Treatment and study plan

Curd Cheese Supplemented Diet

Dietary Supplement

This intervention consists of daily consumption of 100 grams of curd cheese as part of a personalized dietary plan for 8 weeks. Curd cheese is consumed at breakfast and integrated into the participants' regular meal plans. The diet is balanced for total energy and macronutrient distribution according to individual nutritional needs. All participants in this arm receive the same type and brand of curd cheese throughout the intervention period.

Primary outcomes

  1. Change in HbA1c Levels

    Time frame: Baseline and after 8 weeks of intervention

    To evaluate the effect of a curd cheese-supplemented diet on glycemic control by assessing changes in HbA1c levels from baseline to the end of the 8-week intervention.

Secondary outcomes

  1. Change in Fasting Glucose

    Time frame: Baseline and after 8 weeks

    To assess short-term glycemic response by measuring fasting blood glucose at baseline and after the 8-week intervention.

  2. Change in Lipid Profile

    Time frame: Baseline and after 8 weeks

    To evaluate the effect of curd cheese supplementation on lipid metabolism by assessing changes in total cholesterol, LDL, HDL, and triglycerides from baseline to the end of the intervention.

  3. Change in Anthropometric Measures

    Time frame: Baseline and after 8 weeks

    To evaluate changes in body mass index (BMI) from the start to the end of the intervention.

  4. Change in Anthropometric Measures

    Time frame: Baseline and after 8 weeks

    To assess changes in body weight from baseline to the end of the intervention.

  5. Change in Anthropometric Measures

    Time frame: Baseline and after 8 weeks

    To evaluate changes in body fat percentage from the beginning to the end of the intervention.

  6. Change in Anthropometric Measures

    Time frame: Baseline and after 8 weeks

    To assess changes in waist circumference from the beginning to the end of the intervention.

Sponsors and collaborators

Lead sponsor

Süleyman Kılıç

Other

Collaborators

  • Halic University

Registry information

Official study title

The Effect of a Diet Intervention Supplemented With Curd Cheese on Anthropometric Measurements, Glycemia, and Lipidemia in Adults Applying to Darıca Healthy Life Center

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jun 30, 2026
Registry last updated
Jun 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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