Allama Iqbal Teaching Hospital, Dera Ghazi Khan
Dera Ghazi Khan, Punjab Province, 32200, Pakistan
NCT Number: NCT07241507
The goal of this clinical trial is to learn whether the type of suturing technique used to close the abdomen after exploratory laparotomy affects the rate of wound complications. Specifically, the study aims to find out if using interrupted sutures results in fewer cases of wound dehiscence (wound reopening) compared to continuous sutures.
The main question the study seeks to answer is:
Does interrupted suturing reduce the frequency of wound dehiscence compared to continuous suturing in patients undergoing exploratory laparotomy?
Researchers will also observe and compare wound infection rates between the two suturing methods.
About 80 adult patients (18-60 years old) undergoing exploratory laparotomy at the Department of General Surgery, DHQ Teaching Hospital, Dera Ghazi Khan, will take part in this study. Participants will be randomly assigned to one of two groups:
Group A: Continuous abdominal closure using No. 1 Vicryl suture
Group B: Interrupted abdominal closure using No. 1 Vicryl suture
All participants will have their baseline characteristics recorded, including age, gender, obesity, diabetes, and smoking status. The surgical technique and postoperative care will follow the hospital's standard protocols. After surgery, patients will be followed for four weeks with weekly clinical assessments to check for wound infection or wound dehiscence.
The hypothesis is that patients whose abdominal wounds are closed with interrupted sutures will have a lower frequency of wound dehiscence compared to those with continuous sutures.
The findings will help guide surgeons on which abdominal closure method provides better wound healing and fewer postoperative complications.
Looking for future studies?
Notify Me18 year–60 year
All sexes
Interventional
Not applicable
Dera Ghazi Khan, Punjab Province, 32200, Pakistan
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
After an exploratory laparotomy continuous suturing using a single thread of Vicryl No. 1 will be used to stitch the incision's fascial layer together, 1 cm distance from wound edges and between each stitch, creating a line of even tension across the wound.
After an exploratory laparotomy, interrupted suturing using a single thread of Vicryl No. 1 will be used to stitch the incision's fascial layer together, 1 cm distance from wound edges and between each stitch. A knot will be tied after each suture is passed through the tissue, and each stitch will be secured with its own knot.
Time frame: From enrollment to 28-days of operation
A partial or total separation of previously approximated wound edges, on clinical examination of surgical wound.
Time frame: From enrollment to 28-days after operation
Presence any features of erythema, pain, pus discharge on examination of surgical wound and new onset fever (> 98.60F)
Allama Iqbal Teaching Hospital
Other Gov
Frequency of Wound Dehiscence and Wound Infection in Continuous Versus Interrupted Suturing for Abdominal Closure in Exploratory Laparotomy
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07451990
Complications Wounds, Infections
Peshawar, KPK, Pakistan
View Trial DetailsNCT07142395
Infections, Laparotomy Closure After Abdominal Surgery
Multan, Punjab Province, Pakistan
View Trial DetailsNCT05804136
Laparotomy Closure After Abdominal Surgery
Ghent, Oost-Vlaanderen, Belgium
View Trial DetailsNCT03773575
Amputation, Amputation; Postoperative, Sequelae
Valhalla, New York, United States
View Trial Details