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NCT Number: NCT06802419

Effect of Continuous Adductor Canal Block Versus Continuous Adductor Canal Block With Additional Infiltration Between The Popliteal Artery and Capsule of The Knee (IPACK) After Arthroscopic Knee Surgeries

This study aims to evaluate the effect of Continuous Adductor Canal Block only versus adding posterior knee block, known as the Infiltration between the Popliteal Artery and Capsule of the Knee (IPACK) block with Continuous Adductor Canal Block (CACB) after arthroscopic knee surgeries.

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Key information

Age range

21 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ain Shams University

Cairo, 11591, Egypt

Location status: Recruiting

Location contact

Mohamed H Shokier, MD

SUB_INVESTIGATOR

Mohamed O Teaima, MD

SUB_INVESTIGATOR

Mohamed S Ahmed, MD

SUB_INVESTIGATOR

Nada E Hussein, Master

CONTACT

[email protected]

00201112449418

Waleed Abdalla, MD

SUB_INVESTIGATOR

About this study

Enhanced recovery after arthroscopic knee surgery is gaining popularity in orthopedic surgeries. Motor preservation with adequate analgesia has become the optimal postoperative goal, enabling earlier physical therapy, faster recovery, and early hospital discharge. Spinal anesthesia for knee arthroscopy has favorable outcome effects compared with general anesthesia. The positive physiological effects of the provided sympathetic blockade with less blood loss, increased leg blood flow, and better initial pain relief explain this.

An ideal nerve block that targets the sensory nerves and spares the motor function can facilitate early ambulation and rehabilitation, a major goal for patients undergoing arthroscopic knee surgery.

A novel technique for posterior knee block, known as the infiltration between the popliteal artery and capsule of the knee (IPACK) block combined with continuous adductor canal block (CACB) would reduce opioid requirements.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age from 21 to 65 years.
  • Both sexes.
  • American Society of Anesthesiologists (ASA) Physical Status Class I to II.
  • Patients with successful spinal anesthesia.
  • Patients scheduled for elective arthroscopic knee surgery for anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) repair.

Exclusion criteria

  • Declining to give written informed consent.
  • History of allergy to the medications used in the study.
  • Contraindications to regional anesthesia (including coagulopathy and local infection).
  • Polytrauma patients having lower limb fractures.
  • Patients with pre-existing myopathy or neuropathy on the operating limb.
  • Patients with diabetes mellitus.
  • Psychiatric disorder.
  • Morbid obesity [body mass index (BMI) > 45kg/m2].
  • Complicated Surgery.

Treatment and study plan

Continuous adductor canal block

Other

Patients will receive continuous adductor canal block.

Continuous Adductor Canal Block with additional Infiltration between The Popliteal Artery and Capsule

Other

Patients will receive Continuous Adductor Canal Block with additional Infiltration between The Popliteal Artery and Capsule of The Knee

Primary outcomes

  1. Degree of pain

    Time frame: 24 hours postoperatively

    The degree of pain will be assessed using the Visual Analogue Scale (VAS). VAS score is determined by measuring the distance (mm) on the 10-cm line between the "no pain" anchor and the patient's mark, providing a range of scores from 0-100. No pain (0-4 mm), mild pain (5-44 mm), moderate pain (45-74 mm), and severe pain (75-100 mm).

Secondary outcomes

  1. Total Nalbuphine consumption

    Time frame: 24 hours postoperatively

    Rescue analgesia will be given when VAS score ≥ 30 mm, in the form of IV injection of 10 mg Nalbuphine. Followed by reassessment of pain after 10 minutes, a second dose of Nalbuphine will be given if still VAS score ≥ 30 mm.

  2. Straight leg rise

    Time frame: 24 hours postoperatively

    Straight leg rise (SLR) will be recorded.

  3. Range of motion

    Time frame: 24 hours postoperatively

    Range of motion (ROM) will be recorded

  4. Rate of complications

    Time frame: 24 hours postoperatively

    Rate of complications like falling will be recorded

Study contacts

Contact information is provided by the study sponsor or research team.

Nada E Hussein, Master

CONTACT

[email protected]

00201112449418

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

A Comparative Study Between the Effect of Continuous Adductor Canal Block Versus Continuous Adductor Canal Block With Additional Infiltration Between The Popliteal Artery and Capsule of The Knee (IPACK) After Arthroscopic Knee Surgeries

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jan 31, 2025
Registry last updated
Jan 31, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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