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Completed

NCT Number: NCT03285347

Effect of Computer-based Cognitive Training on Attention and Executive Functions in Patients With Parkinson's Disease

The current study adresses the effect of two different computer-based cognitive trianing programmes on attention and executive functions in patients with Parkinson's disease.

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Key information

Conditions

Parkinson Disease Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Executive Dysfunction Movement Disorders Nervous System Diseases Neurodegenerative Diseases Parkinsonian Disorders Synucleinopathies

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bispebjerg Hospital

Copenhagen, Capital Region, 2400, Denmark

About this study

The current study adresses the effect of two different computer-based cognitive training programmes (Brain+ Evolution and Scientific Brain Training PRO) on attention and executive functions in patients with Parkinson's disease. The patients are assigned to one of three groups. Two training groups with each their programme, and a control Group. The training groups will train at home for 8 weeks with follow-ups every second week. The control group will not train at home, but will also receive a follow-up with computer-based stimuli (computerized Card game) every second week, to minimize the possibility that a possible effect is due to the follow-up's with a professional, and not due to the computer training at home.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with Parkinson's disease AND
  • Montreal cognitive assesment (MOCA)-score between 22-28
  • Motorically cabable of using an iPad
  • Not receiving antipsychotic medicine
  • No comorbid diseases which might influence the level of executive functioning, for an example ADHD or acquired brain damage

Exclusion criteria

  • People without Parkinson's disease
  • Parkinson's patients not included in the above inclusion criteria

Treatment and study plan

Computer-based cognitive training

Device

Computer-based cognitive programmes are computer programmes designed as games with the aim of training patients in certain cognitive domains.

Primary outcomes

  1. SDMT

    Time frame: 2 minutes

    Symbol digit modalities test, neuropsychological test of processing speed

  2. PDQ-39

    Time frame: 20 minutes

    Parkinson's disease questionnaire; daily functioning and well-being in Parkinson's disease

Secondary outcomes

  1. HADS

    Time frame: 10 minutes

    Hospital anxiety and depression screening

  2. Digit span

    Time frame: 10 minutes

    Digit span Wais-IV; Working memory

  3. Verbal fluency

    Time frame: 3 minutes

    S-Words, animal-names and A/F-words

  4. Stroop colour/word test

    Time frame: 3 minutes

    Stroop colour/Word test, respone inhibition

  5. Trail Making A and B

    Time frame: 5 minutes

    Trail Making A and B, cognitive flexibility

Sponsors and collaborators

Lead sponsor

Bispebjerg Hospital

Other

Registry information

Official study title

The Effect of Computer-based Cognitive Training on Attention and Executive Functions in Patients With Parkinson's Disease

Important dates

Study start
2017
Primary completion
2020
Study completion
2020
First posted
Sep 18, 2017
Registry last updated
Jan 26, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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